Results 91 to 100 of about 725,720 (244)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Is timing as critical for repair of dextro-transposition of the great arteries with ventricular septal defect without outflow tract obstruction?Central MessagePerspective

JTCVS Open
Objective: We sought to explore the role of timing on outcomes of the arterial switch operation + ventricular septal defect closure. Methods: Neonates undergoing the arterial switch operation + ventricular septal defect closure from the Pediatric Health ...
Muhammad Faateh, MBBS, Spencer Hogue, BS, Amir Mehdizadeh-Shrifi, MD, Kevin Kulshrestha, MD, MBE, Md Monir Hossain, PhD, David G. Lehenbauer, MD, David L.S. Morales, MD, Awais Ashfaq, MD   +7 more
doaj   +1 more source

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

Stambiųjų kraujagyslių transpozicija ir arterijų sukeitimo operacijos: mūsų patirtis

Lietuvos Chirurgija, 2007
Kęstutis Lankutis1, Virgilijus Lebetkevičius2, Virgilijus Tarutis2, Vidmantas Žilinskas2, Sigitas Čibiras2, Rita Sudikienė1, Daina Liekienė2, Vytautas Sirvydis2 1 Vilniaus universiteto ligoninės Santariškių klinikų Širdies chirurgijos centras ...
Kęstutis Lankutis, Virgilijus Lebetkevičius, Virgilijus Tarutis, Vidmantas Žilinskas, Sigitas Čibiras, Rita Sudikienė, Daina Liekienė, Vytautas Sirvydis   +7 more
doaj  

The Impact of Length of Post-Operative Ventilator Support on Outcome of the Arterial Switch Operation - Report from a Single Institute

, 2011
Background: The arterial switch operation (ASO) is the gold- standard surgical procedure for transposition of the great arteries (TGA) in newborns and small infants. The goal of this current study is to describe the postoperative respiratory care and the
呂碧瑛;吳惠東;王景甲;吳恩婷;黃書健;柯文哲;陳益祥;張重義;邱英世;王主科;吳美環, LEU, BEAH-YING;WU, HUEY-DONG;WANG, CHING-CHIA;WU, EN-TING;HUANG, SHU-CHIEN;KO, WEN-JE;CHEN, YIH-SHARNG;CHANG, CHUNG-I;CHIU, ING-SH;WANG, JOU-KOU;WU, MEI-HWAN   +1 more
core  

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Synchronization‐Dissipation in the Cardiorespiratory System

Advanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border, Alain Nogaret, Andrew Lefevre, Vishal Jain   +3 more
wiley   +1 more source

A Versatile‐Designable Framework for Active and Programmable Shape‐Morphing Soft Matter Systems: From Inverse Design to Closed‐Loop Control

Advanced Science, EarlyView.
A versatile framework integrates addressable electrothermal actuation and strain‐constraint mechanisms to construct programmable shape‐morphing soft matter systems. By combining an analytical inverse design strategy for high‐fidelity 3D surface reconstruction with deep learning‐based closed‐loop control, this approach enables zero‐energy shape locking,
Kai Liu, Peiling Xie, Ruitong Song, Banghan Liu, Rui Guo, Jiu‐an Lv   +5 more
wiley   +1 more source

The actions of human atrial natriuretic factor on hepatic arterial and portal vascular beds of the anaesthetized dog [PDF]

, 1990
1. The vascular actions of atrial natriuretic factor (ANF) have been assessed with other vasoactive agents on the hepatic arterial and portal vascular beds of the anaesthetized dog. 2.
Dhume, V. G., Withrington, P. G., Croxton, R., Gerbes, Alexander L.   +3 more
core   +1 more source