Results 51 to 60 of about 7,003 (257)

Arterial switch operation for a complex transposition of the great arteries in dextrocardia [PDF]

European Journal of Cardio-Thoracic Surgery, 2005
A very rare case of a newborn with dextrocardia, complete transposition of the great arteries {S,D,D}, ventricular septal defect, aortic arch hypoplasia, juxtaposition of the morphologically right atrial appendage and superoinferior ventricles is herein presented.
Oppido G, Napoleone CP, Luca R, GARGIULO, GAETANO DOMENICO   +3 more
openaire   +3 more sources

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

Is timing as critical for repair of dextro-transposition of the great arteries with ventricular septal defect without outflow tract obstruction?Central MessagePerspective

JTCVS Open
Objective: We sought to explore the role of timing on outcomes of the arterial switch operation + ventricular septal defect closure. Methods: Neonates undergoing the arterial switch operation + ventricular septal defect closure from the Pediatric Health ...
Muhammad Faateh, MBBS, Spencer Hogue, BS, Amir Mehdizadeh-Shrifi, MD, Kevin Kulshrestha, MD, MBE, Md Monir Hossain, PhD, David G. Lehenbauer, MD, David L.S. Morales, MD, Awais Ashfaq, MD   +7 more
doaj   +1 more source

Ductal recanalization and stenting for late presenters with TGA intact ventricular septum

Annals of Pediatric Cardiology, 2011
Introduction: The ideal management strategy for patients presenting late with transposition of great arteries (TGA), intact ventricular septum (IVS), and regressed left ventricle (LV) is not clear.
Shyam S Kothari, Sivasubramanian Ramakrishnan, Nagendra Boopathy Senguttuvan, Saurabh Kumar Gupta, Akshay K Bisoi   +4 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Transposition of Great Arteries with Left Main Coronary Artery Atresia—Case Report

The Thoracic & Cardiovascular Surgeon Reports, 2018
Background The coronary artery anatomy in patients with transposition of the great artery (TGA) is a contributing factor for outcome in arterial switch procedure.
Ahmed F. Elmahrouk, Tamer Hamouda, Mohamed F. Ismail, Ahmed Jamjoom   +3 more
doaj   +1 more source

Critical Neonatal Congenital Heart Disease – a Rare Complication after Successful Surgical Correction

Journal of Cardiovascular Emergencies, 2020
Pulmonary arterial hypertension (PAH) is a rare but severe complication that should be investigated in patients diagnosed with transposition of the great arteries who have undergone neonatal arterial switch operation.
Şuteu Carmen Corina, Muntean Iolanda, Blesneac Cristina, Pop Marian, Togănel Rodica   +4 more
doaj   +1 more source

Midterm results after complete surgical correction of transposition of the great arteries [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2014
Introduction. Arterial switch operation (ASO) is a cardiosurgical method of choice for complete anatomical correction of transposition of great arteries.
Parezanović Vojislav, Mrđen Mirko, Ilić Slobodan, Vulićević Irena, Đukić Milan, Jovanović Ida, Stefanović Igor, Ilisić Tamara, Kalanj Jasna, Mimić Branko, Milovanović Vladimir   +10 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Acquired origin of the left anterior descending coronary artery from the pulmonary artery: A complication of the arterial switch operation

Annals of Pediatric Cardiology, 2011
The prevalence of coronary anomalies in the transposition of the great arteries is high. Transfer of the coronary arteries during arterial switch operation is the principle step and incomplete transport of the coronary arteries to the neoaortic root ...
Saltik Levent, Baris Safa, Ozyilmaz Isa, Eroglu Ayse   +3 more
doaj