Results 51 to 60 of about 1,239,872 (342)

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao   +7 more
wiley   +1 more source

Morphology of the canine omentum, part 1: arterial landmarks that define the omentum [PDF]

open access: yes, 2016
Although the omentum remains an enigmatic organ, research during the last decades has revealed its fascinating functions including fat storage, fluid drainage, immune activity, angiogenesis and adhesion.
Barone   +30 more
core   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

Determinant of Bronchoarterial Ratio in a Patient Undergoing Computed Tomography Chest

open access: yesJournal of Nobel Medical College
Background: Respiratory diseases pose a significant challenge in Nepali clinical settings due to elevated smoking rates and environmental risks. This study explores the structural changes in conditions such as asthma, chronic obstructive pulmonary ...
Amrendra Kumar Mahato   +5 more
doaj   +1 more source

Patrolling Mechanics of Non-Classical Monocytes in Vascular Inflammation

open access: yesFrontiers in Cardiovascular Medicine, 2017
Non-classical monocytes have emerged as the preeminent vascular housekeepers. Continuous intravascular screening is enabled by slow patrolling on the endothelium and allows a rapid response to local perturbations.
Konrad Buscher   +4 more
doaj   +1 more source

Variations in the Origins of Inferior Phrenic Arteries—An Evaluation with 256 Slice Multidetector Computed Tomography

open access: yesJournal of Clinical Interventional Radiology ISVIR, 2020
Aim To evaluate the frequency and pattern of variations in the origins of right inferior phrenic artery (RIPA) and left inferior phrenic artery (LIPA) on 256 slice multidetector computed tomography (MDCT).
Chinmay Bhimaji Kulkarni   +4 more
doaj   +1 more source

Current Strategy in Endovascular Management for Below-the-Knee Arterial Lesions

open access: yes대한영상의학회지, 2021
The below-the-knee arterial tree is the thinnest of all the leg vessels and is an important path for blood flow to the foot. Hence, lesions including stenosis, especially obstruction, may lead to critical limb ischemia which represents the most severe ...
Kyosoo Hwang, Sang Woo Park
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Occipital artery ⁃ posterior inferior cerebellar artery bypass for the treatment of vertebral aneurysms involving posterior inferior cerebellar artery

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2021
Objective To assess the efficacy of occipital artery (OA)⁃posterior inferior cerebellar artery (PICA) bypass for the treatment of vertebral aneurysms involving PICA.
CHEN Hao   +5 more
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

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