Results 81 to 90 of about 2,316,934 (430)

Physiologic compliance in engineered small-diameter arterial constructs based on an elastomeric substrate. [PDF]

open access: yes, 2009
Compliance mismatch is a significant challenge to long-term patency in small-diameter bypass grafts because it causes intimal hyperplasia and ultimately graft occlusion.
Abbott   +50 more
core   +1 more source

Physiologic Cyclical Load on Inguinal Hernia Scaffold ProFlor Turns Biological Response into Tissue Regeneration

open access: yesBiology, 2023
Surgical repair of groin protrusions is one of the most frequently performed procedures. Currently, open or laparoscopic repair of inguinal hernias with flat meshes deployed over the hernial defect is considered the gold standard.
Giuseppe Amato   +10 more
doaj   +1 more source

Microglial reprogramming: a potential new frontier in enhancing immunotherapy for melanoma brain metastasis

open access: yesMolecular Oncology, EarlyView.
Microglia act as tumor suppressors during brain metastasis colonization but shift to a tumor‐promoting role after melanoma brain metastases form. NF‐κB/RelA signaling emerges as a key driver of this phenotypic shift. Targeting this pathway reprograms microglia into a pro‐inflammatory state, enhancing antitumor immunity and immune checkpoint inhibitor ...
Noam Savion‐Gaiger   +2 more
wiley   +1 more source

On the mechanical stability of growing arteries [PDF]

open access: yes, 2010
Arteries are modeled, within the framework of nonlinear elasticity, as incompressible two-layer cylindrical structures that are residually stressed through differential growth.
Goriely, A., Vandiver, R.
core   +1 more source

Magnetic Resonance Imaging and Computed Tomography for the Noninvasive Assessment of Arterial Aging: A Review by the VascAgeNet COST Action

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Magnetic resonance imaging and computed tomography allow the characterization of arterial state and function with high confidence and thus play a key role in the understanding of arterial aging and its translation into the clinic.
Elisabetta Bianchini   +6 more
doaj   +1 more source

Segmentation and Vascular Vectorization for Coronary Artery by Geometry-based Cascaded Neural Network [PDF]

open access: yesarXiv, 2023
Segmentation of the coronary artery is an important task for the quantitative analysis of coronary computed tomography angiography (CCTA) images and is being stimulated by the field of deep learning. However, the complex structures with tiny and narrow branches of the coronary artery bring it a great challenge.
arxiv  

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Associations of Perirenal Fat Thickness with Renal and Systemic Calcified Atherosclerosis. [PDF]

open access: yes, 2020
BackgroundWe investigated associations between perirenal fat thickness and atherosclerotic calcification in six different vascular beds.MethodsUsing a community-based cohort (n=3,919), perirenal fat thickness was estimated from computed tomography scans.
Allison, Matthew A   +4 more
core  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Visceral artery aneurysms – classification, diagnosis and treatment

open access: yesJournal of Ultrasonography, 2018
Although visceral artery aneurysms are rare, mortality due to their rupture is high, estimated at even 25–75%. That is why it is significant to detect each such lesion.
Ewa Piasek   +6 more
doaj   +1 more source

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