Results 141 to 150 of about 3,325,239 (359)

CHA2DS2-VASc score as a mortality predictor in acute heart failure with preserved ejection fraction

open access: yesFrontiers in Cardiovascular Medicine
BackgroundThe mortality rate in decompensated heart failure (HF) with preserved ejection fraction (HFpEF) remains high. In recent years the prognostic role of CHA2DS2-VASc score, initially formulated for embolic risk prediction in atrial fibrillation ...
Olaf Kądzioła   +17 more
doaj   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez   +10 more
wiley   +1 more source

Preventive percutaneous coronary intervention versus optimal medical therapy for vulnerable plaque: a meta-analysis

open access: yesBMC Cardiovascular Disorders
Background The effectiveness and safety of preventive percutaneous coronary intervention (PCI) on non-flow limiting vulnerable coronary plaque remain uncertain.
Yating Chen   +8 more
doaj   +1 more source

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos   +9 more
wiley   +1 more source

Quantification of coronary artery calcium using ultrafast computed tomography.

open access: yesJournal of the American College of Cardiology, 1990
A. Agatston   +10 more
semanticscholar   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle   +4 more
wiley   +1 more source

Image-based Quantification of 3D Morphology for Bifurcations in the Left Coronary Artery: Application to Stent Design [PDF]

open access: yes, 2016
Background Improved strategies for stent‐based treatment of coronary artery disease at bifurcations require a greater understanding of artery morphology.
Ellwein, Laura M.   +5 more
core   +1 more source

Reversible middle cerebral artery occlusion without craniectomy in rats.

open access: yesStroke, 1989
Enrique Zea Longa   +3 more
semanticscholar   +1 more source

Inflammatory markers guide early risk stratification and prognosis in elderly patients with acute myocardial infarction

open access: yesScientific Reports
High-sensitivity C-reactive protein (hs-CRP) has been associated with prognosis in acute myocardial infarction (AMI) patients, but data on its role in elderly individuals remains limited.
XiaoLong Lin   +5 more
doaj   +1 more source

Response to Allopurinol and Febuxostat According to the Fractional Excretion of Urate in Men With Gout

open access: yesArthritis Care &Research, EarlyView.
Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette   +13 more
wiley   +1 more source

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