Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun+15 more
wiley +1 more source
Small intestinal necrosis caused by the embolism of the superior mesenteric artery after percutaneous vertebroplasty: a case report and analysis of the causes. [PDF]
Zhang W, Lv Q, Yang S, Liang Q.
europepmc +1 more source
Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge+10 more
wiley +1 more source
Carotid artery stenting for a carotid web revealed by shape change after adherent thrombus resolution following conservative treatment. [PDF]
Kimura S+6 more
europepmc +1 more source
The State of High‐Resolution Imaging of the Human Inner Ear: A Look Into the Black Box
High‐resolution imaging of the cochlea is challenged by numerous unique aspects of this organ, where sensorineural cells, crucial for hearing, are too small for conventional modalities like magnetic resonance imaging and computed tomography. This article reviews current imaging techniques, emerging technologies, and innovations aimed at improving ...
Shelley Batts+3 more
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A Caseof Aneurism by Anastomosis in the Left Orbit, Cured by Tying the Common Trunk of the Left Carotid Artery [PDF]
William Dalrymple
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Single‐cell RNA sequencing of lymph node (LN) samples is performed, and a comprehensive landscape of the entire ecosystem is generated. Paracrine orchestration of TME remodeling induced by GLO1 potentiates LN metastasis in breast cancer. This study offers novel perspectives on the microenvironment remodeling of breast cancer LN metastases, suggesting ...
Jindong Xie+16 more
wiley +1 more source
CASE OF ERECTILE TUMOUR OF THE ORBIT, CURED BY INFILTRATION WITH THE SOLUTION OF THE LACTATE OF IRON AND PUNCTURE WITH HOT NEEDLES, AFTER THE LIGATURE OF THE CAROTID ARTERY HAD FAILED; [PDF]
Daniel Brainard
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Large and Giant Intracranial Aneurysm: Surgical Management and Outcomes in a Tertiary Hospital. [PDF]
Barbarawi MM+5 more
europepmc +1 more source
Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization
This study presents a novel approach to enhance stromal cell therapy for myocardial infarction by combining OLED‐based photobiomodulation (OPBM) preconditioning with 3D spheroid culture of hADSCs. The engineered spheroids improve angiogenesis, arterialization, and cardiac function in vivo, offering a next‐generation therapeutic strategy to overcome ...
Yu‐Jin Kim+12 more
wiley +1 more source