Results 281 to 290 of about 3,603,562 (358)

Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity

open access: yesAdvanced Science, EarlyView.
This study highlights that ITGA8 impacts pericyte morphology and function, both crucial for BBB integrity, via RhoA/ROCK signaling, thus influencing TGF‐β1 activation through cytoskeletal tension and ECM interactions. Notably, in post‐ischemic recovery models, ITGA8 deficiency exacerbates vascular dysfunction by impairing pericyte‐mediated BBB ...
Chang‐Xiong Gong   +16 more
wiley   +1 more source

Phenylephrine-induced vasoconstriction of the rat superior mesenteric artery is decreased after repeated swimming

open access: diamond, 2004
Agnaldo Bruno Chies   +4 more
openalex   +2 more sources

Risk factors for coronary artery disease in non-insulin dependent diabetes mellitus: United Kingdom prospective diabetes study (UKPDS: 23)

open access: yesBritish medical journal, 1998
R. Turner   +6 more
semanticscholar   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

open access: yesAdvanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu   +15 more
wiley   +1 more source

Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease.

open access: yesNew England Journal of Medicine, 2016
F. Dewey   +25 more
semanticscholar   +1 more source

ATF5‐Dependent GDF15 Expression Mediates Anesthesia‐Induced Neuroprotection Against Stroke

open access: yesAdvanced Science, EarlyView.
Anesthesia‐induced preconditioning protects against perioperative stroke. By manipulating ATF5 in excitatory neurons, it is shown that anesthesia‐driven ATF5 upregulation activates the mitochondrial unfolded protein response (UPRmt) and elevates GDF15 expression.
Xianshu Ju   +11 more
wiley   +1 more source

Hepatic artery pseudoaneurysms: Two cases, 2 novel solutions, and a brief review of current treatments. [PDF]

open access: yesRadiol Case Rep
Cacciatore J   +5 more
europepmc   +1 more source

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