Targeting miRNA‐1a and miRNA‐15b: A Novel Combinatorial Strategy to Drive Adult Cardiac Regeneration
The article explores a novel therapeutic strategy for cardiac regeneration by targeting miRNA‐1a and miRNA‐15b. Combinatorial inhibition of miR‐1a and miR‐15b enhances cardiomyocyte proliferation, improves heart function, and reduces fibrosis in myocardial infarction models.
Ting Yuan+16 more
wiley +1 more source
Incidence of ocular ischemic syndrome in patients with asymptomatic severe internal carotid artery stenosis. [PDF]
Hou Y+6 more
europepmc +1 more source
Uncover Hidden Physical Information of Soft Matter by Observing Large Deformation
Detecting internal abnormalities in soft matter remains challenging due to its heterogeneous nature. This study introduces a method that infers hidden physical properties by matching observed deformation with simulation through parallel Bayesian optimization.
Huanyu Yang+9 more
wiley +1 more source
Unveiling the link: Takayasu arteritis manifesting as posterior reversible encephalopathy syndrome. [PDF]
Manickavasagam S+3 more
europepmc +1 more source
In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han+10 more
wiley +1 more source
Modeling and simulation of blood flow in unhealthy elliptic arteries with computational fluid dynamics approach. [PDF]
Wahab A, Asjad MI, Riaz MB, Haider JA.
europepmc +1 more source
The roentgen diagnosis of calcified aneurysms of the splenic and renal arteries.
J R Von Ronnen
openalex
Engineering the Immune Response to Biomaterials
This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam+12 more
wiley +1 more source
Alternative 'block and delivery' approach for alcohol septal ablation in hypertrophic cardiomyopathy with ischemia: a case report. [PDF]
Iqbal SMM+6 more
europepmc +1 more source
Novel carbon‐11 labeled pyrimidine derivatives are developed as PET imaging probes for visualizing sigma‐1 receptors in the brain. [11C]CNY‐01 demonstrates superior brain uptake and binding specificity in both rodents and non‐human primates. The study reveals decreased sigma‐1 receptor expression in Alzheimer's disease, offering a promising tool for ...
Ping Bai+12 more
wiley +1 more source