Results 91 to 100 of about 565,274 (298)
Advanced Science, EarlyView.A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu +7 more
wiley +1 more source
Advanced Science, EarlyView.Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He +10 more
wiley +1 more source
EFFECTIVENESS OF HAEMORRHOIDAL ARTERY LIGATION VIA PALPATORY
Pakistan Armed Forces Medical Journal, 2020 Objective: To determine the effectiveness of the haemorrhoidal artery ligation via palpatory method among patients with grade II and III hemorrhoids. Study Design: Observational prospective study.
Hassan Shabbir +6 more
doaj
Experimental Study on Ligation of Hepatic Artery for Cirrhosis of the Liver. Part Ⅰ. Study on Hepatic Artery Ligation in Normal Rat [PDF]
, 1958 1) The effect of hepatic artery ligation is different depending on the site of ligation. A mortality rate decreases in order of the case of ligation of coeliac artery, of hepatic artery distal to its junction with gastroduodenal artery, and proximal to ...
Yamada, Sadamu
core
Advanced Science, EarlyView.SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang +9 more
wiley +1 more source
POST THYROIDECTOMY HYPOCALCEMIA � DOES ARTERIAL LIGATION PLAY A SIGNIFICANT ROLE?
Pakistan Armed Forces Medical Journal, 2008 Objective: The aim of this study was to determine if bilateral inferior thyroid artery (ITA) ligation is a causal factor for the occurrence of postoperative hypocalcaemia after subtotal thyroidectomy. Study design: Quasi experimental trial.
Jahangir Sarwar Khan +3 more
doaj +2 more sources
The bony carotid canal narrows after carotid artery ligation.
, 2021 (A) shows the carotid canal area measured in seven patients who underwent carotid artery ligation. The area decreases continuously over years in all cases, with relative changes of 12.2%–28.9%, demonstrating carotid canal plasticity.
Yuji Agawa (11840779) +8 more
core +1 more source
Advanced Science, EarlyView.NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu +10 more
wiley +1 more source
Advanced Science, EarlyView.A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang +10 more
wiley +1 more source
The Ligation of the Great Arteries [PDF]
Nature, 1892 THIS work is the result of investigations carried out by the authors during the last seven years, and contains the results of long and careful study. The authors were evidently desirous of getting to the bottom of their subject, and in their endeavours to do so, have used every method of research at their disposal.
openaire +1 more source