Results 161 to 170 of about 2,791 (213)

Refractory Relapsing–Remitting Adult‐Onset Still's Disease in an Adolescent Female: A Rare Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Adult‐onset Still's disease (AOSD) is a rare systemic autoinflammatory condition that presents with symptoms such as episodic fevers, a transient rash, inflammatory arthritis, and significant systemic inflammation. Diseases that have a relapsing–remitting clinical course can be challenging to diagnose and treat. We present a case of an 18 year
Tasnim Nafian, Mohd. Mujtaba Akib Bhuiyan, Kazi Ali Aftab, Khaled Mahbub Murshed, Md. Abul Kalam Azad   +4 more
wiley   +1 more source

From Bone Pain to Severe Renal Symptoms: The Journey of a Patient With Multiple Myeloma and Brucellosis (Case Report)

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT In endemic regions, markedly elevated Brucella serologic titers with a dynamic decline after treatment support true infection even in the presence of monoclonal gammopathy. Concurrent infectious and malignant processes should be considered in patients presenting with severe renal failure and overlapping systemic symptoms to avoid diagnostic ...
Maryam Ghaffari Rahbar, Tahere Zarouk Ahimahalle, Marziyeh Ghalamkari, Maedeh Olya   +3 more
wiley   +1 more source

Exposure–Response Relationship of Dostarlimab in Primary Advanced/Recurrent Endometrial Cancer: Results From Interim Analysis 2 of Part 1 of the RUBY Trial

Clinical Pharmacology in Drug Development, Volume 15, Issue 8, August 2026.
Abstract Dostarlimab in combination with carboplatin–paclitaxel was approved for primary advanced or recurrent endometrial cancer (pA/rEC). The first interim analysis (IA1) of RUBY Part 1 (NCT03981796) showed no significant exposure–response (ER) relationship for progression‐free survival or for the five most common dostarlimab‐related adverse events ...
Mita Kuchimanchi, Trine Lembrecht Jørgensen, Eva Hanze, Angela Jain, Oskar Alskär, Oleksandr Zub, Mark S. Shahin, Anthoula Koliadi, Bhavana Pothuri, Thomas Krivak, Mikalai Pishchyk, Yakir Segev, Floor J. Backes, Christine Gennigens, Sara Bouberhan, Stefan Zajic, Murad Melhem, Joseph Buscema   +17 more
wiley   +1 more source

SARS‐CoV‐2 Spike Peptides Trigger Nociceptive Responses Through Spinal TLR4 Pathways

European Journal of Pain, Volume 30, Issue 7, August 2026.
ABSTRACT Background Pain is a common neurological manifestation of COVID‐19, yet the mechanisms by which SARS‐CoV‐2 spike protein fragments contribute to nociceptive processing remain poorly understood. We investigated whether spike‐derived peptides directly activate spinal neuroimmune pathways involved in pain signalling.
Bruno Eduardo Silva, Rayner Ribeiro Cardoso, Lívia Maria Ribeiro Rosário, João Paulo Prado, Rafaela Silva dos Santos, Flávio Protasio Veras, Mylena de Souza, Eduardo Maffud Cilli, Danilo Olivier, Marco Antonio de Andrade Belo, Ives Charlie‐Silva, Ester Siqueira Caixeta, Angel Roberto Barchuk, Albená Nunes‐Silva, Thiago Roberto Lima Romero, Giovane Galdino   +15 more
wiley   +1 more source

Clinicopathological Features of Lupus Erythematosus Panniculitis (LEP): A Retrospective Analysis of 54 Cases

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Lupus Erythematosus Panniculitis (LEP) is a rare subtype of Cutaneous Lupus Erythematosus. It is a challenging disease to diagnose and treat due to limited understanding of its clinical and histopathological characteristics. Methods We conducted a retrospective review of 54 biopsy‐proven LEP cases evaluated at a dermatology referral
Maryam Nasimi, Narjes Ramezani, Kambiz Kamyab, Alireza Abdshah, Maryam Ghiasi, Sahar Montazeri, Hanie Babaie, Fatemeh Saberi   +7 more
wiley   +1 more source

A Prospective Observational Study of Anamorelin During Chemoimmunotherapy in Non‐Small Cell Lung Cancer With Cachexia (SPIRAL‐ANA)

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background The prognosis of patients with advanced non‐small cell lung cancer (NSCLC) complicated by cancer cachexia remains poor. Anamorelin, a ghrelin receptor agonist, has been approved only in Japan for the treatment of cancer cachexia.
Kenji Morimoto, Junji Uchino, Makoto Hibino, Yuki Takeyasu, Ken Yamamoto, Yoshie Morimoto, Yusuke Chihara, Takayuki Nakano, Hiroyasu Kaneda, Shunya Tanaka, Shinsuke Ogusu, Yasuhiro Goto, Takashi Nomizo, Takayo Ota, Hiroaki Tsukamoto, Yoshizumi Takemura, Katsumi Nakatomi, Hayato Koba, Kohei Yoshimine, Takayuki Shimose, Tadaaki Yamada, Koichi Takayama   +21 more
wiley   +1 more source

Genomic and Epidemiological Characterization of DENV‐1 and DENV‐2 Co‐Circulation During the 2023–2024 Dengue Epidemic in Espírito Santo, Brazil

Journal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT In 2023 and 2024, Espírito Santo state, Brazil, experienced its largest dengue epidemic in 30 years, with record numbers of cases and deaths. This study aimed to characterize confirmed dengue cases and the dengue virus (DENV) during the epidemic and pre‐epidemic periods.
Nicolli Ribeiro de Jesus, Caio Santos de Souza, Mariene R. Amorim, João Paulo Cola, Raquel Gomes Catozo, Bruno Luiz M. Guedes, Bruna Caetano Pimenta, Julia Sthefany Nunes Zordan, Yasmim Barcellos Madeira Rosa, Henrique Tamanini Silva Moschen, Aline Souza Areias, Tatiane Comerio, Isabela Valim Sarmento, Julia Miranda Fardin, Daniel Claudio de Oliviera Gomes, Kiven Kumar, Eng Eong Ooi, Camila Malta Romano, Creuza Rachel Vicente   +18 more
wiley   +1 more source

Identification of Clinical Factors Associated With the Immunogenicity of Homologous ChAdOx1‐nCoV‐19 Vaccine in Hemodialysis Patients

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 8, August 2026.
ABSTRACT Hemodialysis (HD) patients are at higher risk of severe COVID‐19 and may exhibit suboptimal vaccine responses. This study evaluates the factors influencing vaccine‐induced immunity in HD patients following the second dose of the Vaxzevria. A total of 276 HD patients and 126 controls were included. Antibody responses were assessed using binding
Chia‐Wei Chang, Ping‐Hsun Wu, Li‐Yun Chang, Yu‐Ying Huang, Teng‐Hui Huang, Su‐Chu Lee, Yi‐wen Chiu, Shang‐Jyh Hwang, Tsun‐Yung Kuo, Mei‐Chuan Kuo   +9 more
wiley   +1 more source

A Serum N‐Glycan Ratio Associated With Disease Severity and Treatment Response in Psoriasis

The Journal of Dermatology, Volume 53, Issue 8, Page 1090-1098, August 2026.
ABSTRACT Psoriasis is a chronic, immune‐mediated inflammatory disease with heterogeneous manifestations. Reliable biomarkers reflecting disease severity and treatment response remain limited. Glycans—carbohydrate structures attached to proteins and lipids—play key roles in biological processes, contributing to functional specificity.
Kentarou Nishimura, Noritaka Oyama, Takumi Hasegawa, Hiroshi Kasamatsu, Takenao Chino, Takahiro Tokunaga, Kiyoshi Higashi, Koichi Saito, Keita Yamada, Minoru Hasegawa   +9 more
wiley   +1 more source

Standardization of postoperative adverse event reporting: A critical opportunity for improvement within the National Clinical Trials Network

Cancer, Volume 132, Issue 15, 1 August 2026.
Beth Helmink, Matthew H. G. Katz, Chandrajit P. Raut, Sumithra J. Mandrekar, Kristina Laumann, Allison Booth, Laura Hoffman, Eric A. Singer, Isabelle Bedrosian, Rebecca A. Snyder   +9 more
wiley   +1 more source