Results 71 to 80 of about 55,752 (265)

Clinical trial of safety and antitumor activity of farletuzumab ecteribulin in patients with platinum‐resistant ovarian cancer: Phase I expansion results

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective In the dose‐escalation part of Study 101, which included multiple tumor types, objective responses were observed in 10 of 22 patients across multiple dose levels of farletuzumab ecteribulin (FZEC). We explored the safety/antitumor activity of FZEC in patients with platinum‐resistant ovarian cancer (PROC) from the Study 101 expansion ...
Kan Yonemori, Mayu Yunokawa, Koji Matsumoto, Kazuhiro Takehara, Kosei Hasegawa, Yasuyuki Hirashima, Hidenori Kato, Hiroki Ikezawa, Yohei Otake, Wataru Yusa, Takuma Miura, Shin Nishio   +11 more
wiley   +1 more source

Clinical Features and Therapeutic Outcomes in Pyoderma Gangrenosum: A Prospective Cohort Study

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis highly associated with systemic comorbidities. Accurate diagnosis and treatment remain challenging due to its rarity and clinical mimickers. Objectives To evaluate demographic, clinical features and treatment outcomes in patients referred with suspected PG at a tertiary ...
David Croitoru, Nesrine Brahimi, Haleh Zabihi, Cathryn Sibbald, Kyle Seigel, Delaram Shojaei, Eric McMullen, Afsaneh Alavi, Lily Archaempong, Aaron M. Drucker, Adam Weizman, Kenneth Croitoru, Robert Inman, Vincent Piguet   +13 more
wiley   +1 more source

Survivin Measurement improves Clinical Prediction of Transition From Arthralgia to RA—Biomarkers to Improve Clinical Sensitivity of Transition From Arthralgia to RA

Frontiers in Medicine, 2018
Background: Arthralgia often predates development of rheumatoid arthritis (RA). A set of joint symptoms commonly found in patients during their transition from arthralgia to RA, has been recently proposed.Aim: To combine clinical and serological markers ...
Malin C. Erlandsson, Malin C. Erlandsson, Minna Turkkila, Rille Pullerits, Rille Pullerits, Rille Pullerits, Maria I. Bokarewa, Maria I. Bokarewa   +7 more
doaj   +1 more source

Risk Factors Associated With the Number of Symptoms and Distress Caused by Genitourinary Syndrome of Menopause in Taiwanese Women

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT A high percentage of women who undergo the transition to postmenopause experience both menopausal symptoms and genitourinary syndrome of menopause (GSM). However, GSM is often underdiagnosed. This research aims to identify risk factors that may influence the number of GSM symptoms and whether they cause distress in Taiwanese women > 45 years ...
Shu‐Fang Su, Chiu‐Lin Wang, Shu‐Yuan Lin   +2 more
wiley   +1 more source

Identification of Clinical Factors Associated With the Immunogenicity of Homologous ChAdOx1‐nCoV‐19 Vaccine in Hemodialysis Patients

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hemodialysis (HD) patients are at higher risk of severe COVID‐19 and may exhibit suboptimal vaccine responses. This study evaluates the factors influencing vaccine‐induced immunity in HD patients following the second dose of the Vaxzevria. A total of 276 HD patients and 126 controls were included. Antibody responses were assessed using binding
Chia‐Wei Chang, Ping‐Hsun Wu, Li‐Yun Chang, Yu‐Ying Huang, Teng‐Hui Huang, Su‐Chu Lee, Yi‐wen Chiu, Shang‐Jyh Hwang, Tsun‐Yung Kuo, Mei‐Chuan Kuo   +9 more
wiley   +1 more source

Autologous minimally manipulated adipose‐derived stromal vascular fraction in knee osteoarthritis: Lasting symptom relief and imaging evidence from a 12‐month prospective study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate the safety and efficacy of intra‐articular autologous transplantation of adipose‐derived connective tissue micrografts rich in stromal vascular fraction (CTM‐SVF), obtained using an enzyme‐free system (Hy‐Tissue® SVF) for knee osteoarthritis (OA). Methods Thirty patients (mean age of 53.3 ± 6.4 years) with Kellgren–Lawrence
Laura Mangiavini, Nicolò Rossi, Riccardo Giorgino, Francesco Borelli, Alessandra Colombini, Paola De Luca, Simona Landoni, Luca Maria Sconfienza, Carmelo Messina, Irene Beriotto, Giuseppe M. Peretti, Laura de Girolamo   +11 more
wiley   +1 more source

Dor articular na osteoartropatia hipertrófica primária: descrição de caso e revisão de tratamento Arthralgia in primary hipertrophic osteoarthropathy: case report and review of the treatment

Revista Brasileira de Reumatologia, 2007
Apresentamos o caso de um paciente com baqueteamento digital e artrite que foi diagnosticado como tendo osteoartropatia hipertrófica primária. Essa é uma doença rara e benigna.
Aldo Lainetti, Fernanda Satake Novaes, Lívia Reis de Miranda, Sílvio Henriques de Lira   +3 more
doaj   +1 more source

Diagnosis and Management of Isolated Laryngeal Sarcoidosis: A Systematic Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective This study reviews the existing literature on patients diagnosed with sarcoidosis isolated to the larynx to improve our understanding of the diagnosis and management of this rare condition. Data Sources Embase, PubMed, Web of Science.
Raj Malhotra, Joseph Celidonio, Nicholas Hamilton, Alexandra Filipkowski, Kenneth Yan, Rachel Kaye   +5 more
wiley   +1 more source

CHILD WITH JOINT PAIN – CLINICAL VIGNETTES

Slovenska pediatrija
Joint pain is a common clinical symptom in children with a broad and diverse etiology – ranging from benign, self-limiting conditions to serious and potentially life-threatening diseases.
Maša Bizjak
doaj   +1 more source

Considerations of race and ethnicity within rehabilitation studies for post COVID‐19 condition: A scoping review

PM&R, EarlyView.
Abstract Post COVID‐19 condition (PCC) or long COVID disproportionately affects racial and ethnic minority communities. There are a growing number of rehabilitation studies for PCC, however, it has yet to be determined whether existing studies take race and ethnicity into account in their study designs and whether existing rehabilitative approaches are
Nadine Akbar, Siona Phadke, Sumaya Mehelay, Abdul Kareem Pullattayil, Afolasade Fakolade, Monica Busse   +5 more
wiley   +1 more source