Results 141 to 150 of about 1,220,899 (350)
Targeted Degradation of sGRP78 Alleviates the Immunosuppressive Tumor Microenvironment
Advanced Science, EarlyView.Soluble GRP78 (sGRP78) is identified as a novel tumor‐derived soluble factor that induces regulatory T cells (Treg). sGRP78 serves as an excellent serological biomarker for predicting the efficacy of neoadjuvant therapy in breast cancer patients. sGRP78 specifically binds to B cells, inducing the expression of IL‐10 and PD‐L1, thereby promoting Treg ...
Zhenghao Wu +10 more
wiley +1 more source
Advanced Science, EarlyView.Punicalagin, a pomegranate molecule, helps the body fight Mycobacterium abscessus. It preferentially boosts interstitial macrophages in the lung, stabilizing mitochondria and switching on the autophagy via SIRT1/FoxO3a, which lowers bacterial load without directly killing bacteria.
Kefan Bi +4 more
wiley +1 more source
Identifying Key Questions and Challenges in Microchimerism Biology
Advanced Science, EarlyView.This study identifies key unanswered questions about microchimerism, the presence of cells from one individual living in another. Experts highlight how these cells may affect health, pregnancy, and disease. This study outlines research priorities and challenges in detecting and studying these rare microchimeric cells, aiming to guide future discoveries
Kristine J. Chua +31 more
wiley +1 more source
Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined
Aggregate, EarlyView.Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei +8 more
wiley +1 more source
Choosing an allograft or autograft in orthopedic surgeries for athletes [PDF]
, 2016 Athletes and their doctors have the choice of using an allograft or autograft in reconstruction surgeries. The purpose of this study is to see if there is a difference in the healing mechanism and surgical outcome in using an allograft or autograft ...
Izzo, Cassandra M
core +1 more source
Frontiers in ImmunologyThis report describes the case of a 48-year-old woman who presented with sternoclavicular joint arthritis after administration of an immune checkpoint inhibitor (ICI), durvalumab, for small cell lung carcinoma. The onset of arthritis transpired 18 months
Shion Kachi +4 more
doaj +1 more source
Advanced Intelligent Systems, EarlyView.In this contribution, it is shown that miniaturized nerve stimulation implants can be used in collaborative networks. Inductive links and ultrasound are combined to supply these implants with energy and data; the advantages and disadvantages of each method, as well as safety risks and possibilities for improvement are discussed and the best ...
Benedikt Szabo +5 more
wiley +1 more source
DePerio: Deep Learning‐Based Oral Inflammatory Load Quantification for Periodontal Applications
Advanced Intelligent Systems, EarlyView.a) Inflammation and oral polymorphonuclear neutrophil (oPMN) Migration: Dental plaque accumulation leads to inflammation, prompting white blood cells (WBCs), particularly oPMNs, to migrate from blood vessels through the gingival epithelium into the oral cavity.
Fatemeh Soheili +9 more
wiley +1 more source
An in vitro study of the replication, morphology and DNA base composition of Mycoplasma ovipneumoniae : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University, New Zealand [PDF]
, 1977 Mycoplasma ovipneumoniae can almost invariably be isolated from the lungs of sheep with chronic pneumonia, which is a prevalent disease in New Zealand hoggets.
Major, Robert Malcolm
core
Lyme arthritis: linking infection, inflammation and autoimmunity
Nature Reviews Rheumatology, 2021 Robert B. Lochhead +4 more
semanticscholar +1 more source