Results 121 to 130 of about 97,243 (208)
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Anti-neutrophil cytoplasmic antibodies in idiopathic inflammatory disorders [PDF]
, 1994 This thesis studies the prevalence of anti-neutrophil cytoplasmic antibodies (ANCA) in idiopathic inflammatory disorders in which GS-ANA were described during the 60s: rheumatoid arthritis, autoimmune liver diseases, inflammatory bowel disease, and ...
Mulder, Alide Heleen Leontine
core +2 more sources
The return of metabolism: biochemistry and physiology of glycolysis
Biological Reviews, EarlyView.ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning +19 more
wiley +1 more source
Disease activity states, reasons for discontinuation and adverse events in 1038 Italian children with juvenile idiopathic arthritis treated with etanercept [PDF]
, 2017 The advent of biologic medications has increased considerably the potential for treatment benefit in juvenile idiopathic arthritis (JIA), with clinical remission being now achievable in a substantial proportion of patients.
A. Civino +27 more
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Clinical Genetics, EarlyView.Whole‐exome sequencing of five families with non‐medullary thyroid cancer revealed three candidate genes. Functional analyses confirmed BCL2L11 as a strong candidate gene for hereditary predisposition to non‐medullary thyroid cancer. ABSTRACT Familial non‐medullary thyroid cancer, defined as two or more affected first‐degree relatives, accounts for 3 ...
Duygu Abbasoglu +9 more
wiley +1 more source
Macrophage activation syndrome in a pediatric patient suffering from Still's disease
Universidad Médica Pinareña, 2019 Introduction: Still's disease in childhood constitutes an inflammatory disorder, of autoimmune origin, which is framed within the group of juvenile idiopathic arthritis, probably being the most peculiar entity of the group.
Laura Elena Blanco de la Portilla +2 more
doaj +2 more sources
Social Functioning of Children and Their Parents: Are They Related? [PDF]
, 2010 This study examined whether parents' social support was related to their children's peer acceptance and likability. The moderating role of the parent's and the child's gender was also examined.
Wetzel, Megan
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How Do Dental Professionals and Students Assess Orthodontic Case Complexity?
European Journal of Dental Education, EarlyView.ABSTRACT Background Accurately diagnosing and assessing orthodontic case complexity is essential for treatment planning, estimating therapy duration, and determining required expertise. Various indices, such as the American Board of Orthodontics Discrepancy Index (ABO DI), provide objective evaluations.
Giulia Semerari +4 more
wiley +1 more source
Osteochondrosis in horses: An overview of genetic and other factors
Equine Veterinary Journal, EarlyView.Abstract Osteochondrosis (OC) is a frequent manifestation of developmental orthopaedic disease, and its severe clinical presentation is known as OC dissecans (OCD). OC is defined as a disruption of the endochondral ossification process in the epiphyseal cartilage, and this disease has been reported in different mammalian species, including humans, dogs,
Lola Martinez‐Saez +2 more
wiley +1 more source