Results 131 to 140 of about 784,373 (290)

Th17 and Th1 Lymphocytes in Oligoarticular Juvenile Idiopathic Arthritis

Frontiers in Immunology, 2019
In the last years much attention has focused on the Th17 and Th1 phenotypes and on their pathogenic role in juvenile idiopathic arthritis, investigating how the cytokines produced by T helper cells act on resident cells on the synovia and which signal ...
L. Maggi, A. Mazzoni, R. Cimaz, F. Liotta, F. Annunziato, L. Cosmi   +5 more
semanticscholar   +1 more source

Epigenetic Clock Analysis of Sex Chromosome Aneuploidies

Aging Cell, EarlyView.
Next‐generation epigenetic clocks indicate lower age acceleration and slower pace of aging in 47,XXY than 46,XX, 46,XY, and 47,XYY. A first‐generation clock (Skin & Blood) indicates higher age acceleration in 47,XXY and 47,XYY than 46,XY, while higher naïve CD8+ T in 47,XXY than both 46,XY and 46,XX suggests reduced immunosenescence.
Joshua Zhang, Jordan Teoli, Benjamin Rey, Cristina Vieira, Jean‐François Lemaitre, Ingrid Plotton, Gabriel A. B. Marais, Steve Horvath   +7 more
wiley   +1 more source

Baricitinib Augments Lonafarnib Therapy to Preserve Colonic Homeostasis and Microbial Balance in a Mouse Model of Progeria

Aging Cell, EarlyView.
Combined baricitinib and lonafarnib treatment improved colonic pathology in LmnaG609G/G609G progeria mice by reducing progerin, maintaining epithelial regeneration, mitigating inflammation and senescence, and preserving microbiome composition. ABSTRACT Hutchinson‐Gilford Progeria Syndrome (HGPS) is a fatal genetic disorder caused by progerin, a mutant ...
Moritz Schroll, Yacine Amar, Peter Krüger, Klaus Neuhaus, Karima Djabali   +4 more
wiley   +1 more source

Biologic‐Induced Paradoxical Psoriatic Alopecia: A Systematic Review

Australasian Journal of Dermatology, EarlyView.
ABSTRACT A systemic review was completed of primary research articles reporting patient outcomes in paradoxical psoriatic alopecia in association with biologic therapy. Our search strategy identified 96 patients from 45 studies in addition to our own case.
Yaron Gu, Deshan F. Sebaratnam, Mani Makhija, Joshua Farrell   +3 more
wiley   +1 more source

Current Validated Clinical and Patient Reported Disease Outcome Measures in Juvenile Idiopathic Arthritis

Open Access Rheumatology: Research and Reviews, 2023
Erin Balay-Dustrude,1,2 Susan Shenoi1,2 1Department of Pediatrics, Division of Rheumatology, University of Washington, Seattle, WA, USA; 2Department of Pediatric Rheumatology, Seattle Children’s Hospital and Research Center, Seattle, WA ...
Balay-Dustrude E, Shenoi S
doaj  

Drug‐Induced Periocular and Ocular Surface Disorders: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Various systemic and topical medications can induce ocular and periocular cutaneous adverse effects (AEs), ranging from mild to severe. These AEs may lead to ocular surface (OS) damage and, in some cases, life‐threatening complications. Drug‐induced ocular adverse reactions are generally classified into two primary categories: toxic reactions ...
Andrea Leonardi, Banu Bozkurt, Diana Silva, Charlotte G. Mortz, Christophe Baudouin, Marina Atanaskovic‐Markovic, Vibha Sharma, Serge Doan, Shweta Agarwal, Daniel Pérez‐Formigo, Maria Joao Vasconcelos, Francoise‐Brignole Baudouin, Gonzalo Chorzepa, Jean‐Luc Fauquert, Virginia Calder, Pascal Demoly, Luis Delgado   +16 more
wiley   +1 more source

Tocilizumab in the treatment of systemic juvenile idiopathic arthritis

Open Access Rheumatology: Research and Reviews, 2012
Miho Murakami,1 Minako Tomiita,2,3 Norihiro Nishimoto11Laboratory of Immune Regulation, Wakayama Medical University, Wakayama, 2Department of Pediatrics, Graduate School of Medicine, Chiba University, Chiba, 3Department of Allergy and Rheumatology, Chiba
Murakami M, Tomiita M, Nishimoto N
doaj  

Temporomandibular joint arthritis in juvenile idiopathic arthritis, now what?

Pediatric Rheumatology Online Journal, 2018
BackgroundArthritis involving the temporomandibular joint (TMJ) complicates 40 - 96% of cases of juvenile idiopathic arthritis (JIA), potentially leading to devastating changes to form and function. Optimal evaluation and management of this joint remains
M. Stoll, C. Kau, P. Waite, R. Cron
semanticscholar   +1 more source

Low ICU Admission and Excellent Outcomes in MIS‐C: A Swedish Study From an Open Society

Acta Paediatrica, EarlyView.
ABSTRACT Aim During the COVID‐19 pandemic, Sweden chose a more open public health approach. A general concern was that this approach would affect the population negatively. We describe the Swedish national MIS‐C cohort and risk factors for severe disease defined as admission to the intensive care unit and cardiogenic shock.
Petra Król, Maria Altman, Stefan Berg, Lillemor Berntson, Petter Brodin, Anders Fasth, Robin Kahn, Jenny Lingman Framme, Maria Mossberg, Charlotta Nordenhäll, Karin Palmblad, André Rudolph, Eva Säve‐Söderbergh, AnnaCarin Horne   +13 more
wiley   +1 more source

Discrimination of acute lymphoblastic leukemia from systemic-onset juvenile idiopathic arthritis at disease onset

Clinics, 2011
OBJECTIVE: To assess clinical and laboratory features that differentiate acute lymphoblastic leukemia from systemic juvenile idiopathic arthritis at disease onset. METHODS: Fifty-seven leukemia patients with musculoskeletal involvement, without blasts on
Mirian S. Tamashiro, Nadia Emi Aikawa, Lucia Maria A. Campos, Lilian Maria Cristofani, Vicente Odone-Filho, Clovis A. Silva   +5 more
doaj   +1 more source