ABSTRACT Introduction Chronic pain affects 1 in 5 adults and children globally; however, management remains highly variable and low value care is common. Inconsistent recommendations among clinical practice guidelines for management of chronic pain contribute to suboptimal patient management.
Andrea J. Darzi +48 more
wiley +1 more source
Evaluation of 5-methylcytosine and 5-hydroxymethylcytosine levels in juvenile idiopathic arthritis and its types. [PDF]
Dogantan S +5 more
europepmc +1 more source
ABSTRACT Background and Aims Hemophilia A and B are two of the most common bleeding disorders. Genetic risk factors are associated with the development of autoantibodies released in hemophilia patients against alternative factors and are the most important problems associated with the care of these patients. Objective In this study, we reviewed genetic
Fatemeh Zeylabi +2 more
wiley +1 more source
ABSTRACT Background Pulmonary complications are a major cause of morbidity and mortality in pediatric and young adult hematopoietic stem cell transplant (HSCT) recipients. The impact of preexisting lung dysfunction on posttransplant outcomes remains understudied. Methods In a multi‐institutional prospective cohort of 444 patients (≤24 years) undergoing
Jane Koo +40 more
wiley +1 more source
The Impact of 24-Month Etanercept Therapy on Changes in Adiponectin, Leptin and Tenascin C Levels in the Blood of Children with Juvenile Idiopathic Arthritis. [PDF]
Siwiec J +5 more
europepmc +1 more source
Evaluating the causal effect of circulating proteome on the risk of Juvenile idiopathic arthritis: an omics pipeline study. [PDF]
Wu X +6 more
europepmc +1 more source
Case Report: Novel <i>UNC93B1</i> variant causes rheumatoid arthritis and interstitial pneumonia. [PDF]
He T +6 more
europepmc +1 more source
Children's experiences of a support program during their first year with juvenile idiopathic arthritis : - Insights from qualitative interviews. [PDF]
Mördrup K +3 more
europepmc +1 more source
Inflammatory osteolysis: A conspiracy against bone [PDF]
Abu-Amer +36 more
core +2 more sources
Biologics and Small‐Molecule Therapies in Netherton Syndrome: A Comprehensive Review
ABSTRACT Netherton syndrome (NS) is a rare congenital ichthyosis caused by loss‐of‐function mutations in the SPINK5 gene, leading to defective expression of the serine protease inhibitor LEKTI. Dysregulated epidermal protease activity results in impaired skin barrier function and chronic inflammation, accompanied by complex immune profiles. NS patients
Shin Morizane +6 more
wiley +1 more source

