Results 101 to 110 of about 50,850 (292)

Inosine‐Triphosphate‐Pyrophosphatase Activity as a Potential Predictor of Methotrexate Remission in Juvenile Idiopathic Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Methotrexate (MTX) is the first‐line therapy for juvenile idiopathic arthritis (JIA), but up to 40% of patients do not respond to it. Low inosine triphosphate pyrophosphatase (ITPA) activity has been associated with reduced clinical remission. We investigated the role and underlying mechanisms of ITPA in vitro. Methods ITPA enzymatic activity
Sofia Sindici Forgiarini, Marianna Lucafò, Debora Curci, Davide Selvestrel, Valentina Moressa, Sofia Pagarin, Barbara Bellich, Martina Franzin, Alberto Tommasini, Mara L. Becker, Laura B. Ramsey, Susan D. Thompson, Carl D. Langefeld, Federica Corba, Edoardo Marrani, Gabriele Simonini, Gabriele Stocco, Giuliana Decorti, Andrea Taddio, Serena Pastore   +19 more
wiley   +1 more source

Safety and Efficacy of Methotrexate for Chinese Adults With Psoriasis With and Without Psoriatic Arthritis. [PDF]

, 2019
Importance It is necessary to determine whether psoriasis responds to methotrexate in the same manner in patients with and without psoriatic arthritis.
Li, Xueying, Wu, Mingshun, Han, Ling, Fang, Xu, Chang, Yuling, Xu, Qiaohu, Huang, Qiong, Qian, Danfeng, Yawalkar, Nikhil, Yan, Kexiang, Zhang, Yuanjing, Jin, Ling, Xu, Jinhua, Zhang, Zhenghua, Zhang, Qun, Zheng, Zhizhong, Zhang, Xuejun   +16 more
core   +1 more source

COVID-19 in patients with psoriasis: A Latin American case series

JAAD International, 2021
Isabela Campo-Slebi, MD, María Fernanda Meza-Corso, MD, Paola Cárdenas, MD, Juan Raúl Castro-Ayarza, MD, Cesar González, MD, Carolina Cortés, MD, Manuel Franco, MD, Fernando Valenzuela, MD   +7 more
doaj   +1 more source

Osteoporosis and Psoriatic Arthritis

The Journal of Rheumatology Supplement, 2012
Osteoporosis (OP) is a skeletal disorder characterized by compromised bone strength that predisposes to an increased risk of fracture. The prevalence of OP in the general population is very high as established in several studies, and OP represents one of the possible aspects of bone involvement in arthritis.
DEL PUENTE, ANTONIO, Esposito A, Parisi A, ATTENO, MARIANGELA, Montalbano S, Vitiello M, Esposito C, Bertolini N, Foglia F, COSTA, LUISA, SCARPA, RAFFAELE   +10 more
openaire   +3 more sources

A Multifaceted Interplay Among Hemophagocytosis, Interleukin‐18, and Type I Interferon Distinguishes Still Disease From Other Autoinflammatory Diseases

Arthritis &Rheumatology, EarlyView.
Objective The unknown pathophysiology and the lack of specific features for systemic juvenile idiopathic arthritis and adult‐onset Still disease (collectively known as Still disease; SD) delay diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory ...
Yvonne M. Mueller, Charlotte Girard, Harmen J. G. van de Werken, Stefan J. Erkeland, Dwin G. B. Grashof, Laurie Vaillant, Renske J. H. den Dekker, Iris van Zuijen, Sharon Veenbergen, Fanny Coffin, Eric Bindels, Yvan Jamilloux, Katerina Laskari, Vassili Soumelis, Bruno Fautrel, Cem Gabay, Peter D. Katsikis   +16 more
wiley   +1 more source

Magnetic resonance imaging of nail unit in psoriatic arthritis. [PDF]

, 2009
The use of magnetic resonance imaging (MRI) has modified the imaging strategies of inflammatory arthritides. In psoriatic arthritis (PsA), MRI study of the nail unit identifies nail involvement that appears as the initial lesion for induction of distal ...
L. Costa, M. Atteno, S. Iervolino, DEL PUENTE, ANTONIO, M. A. Cimmino, F. Caso, E. Soscia, M. Salvatore, R. Scarpa, C. Sirignano, A. S.o.r.i.c.e.l.l.i., PELUSO, ROSARIO   +11 more
core   +1 more source

Health professional views on the assessment and management of foot problems in people with psoriatic arthritis in Australia and New Zealand: a qualitative investigation

BMC Musculoskeletal Disorders, 2019
Background Active foot disease persists in a high proportion of people with psoriatic arthritis despite the availability of pharmacological and non-pharmacological interventions to modify the course of the disease.
Kate Carter, Steven Walmsley, Keith Rome, Deborah E. Turner   +3 more
doaj   +1 more source

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola, Philip Mease, Alan Kivitz, Naveed Sattar, Laura C. Coates, Daniel Aletaha, Cynthia E. Kartman, Peter Fischer, Luna Sun, Píndaro Martínez‐Osuna, Andris Kronbergs, Purvi Prajapati, Anabela Cardoso, Mark C. Genovese, Alexis Ogdie   +14 more
wiley   +1 more source

S100A8/A9 in psoriatic plaques from patients with psoriatic arthritis [PDF]

, 2016
Objective: To evaluate levels of the calcium-binding proteins S100A8 and S100A9 in the skin of patients with psoriatic arthritis. Methods: Skin punch biopsies were obtained from patients with psoriatic arthritis and healthy control subjects.
Conigliaro, Paola, Maria Sole Chimenti, Paola Conigliaro, Costanzo, A, Triggianese, Paola, Conigliaro, P, Perricone, R, Giunta, Alessandro, Roberto Perricone, Botti, E, Costanzo, Antonio, Giunta, A, Costanzo, A., Antonio Costanzo, NARCISI, ALESSANDRA, Chimenti, MS, Teoli, Miriam, Triggianese, P, Elisabetta Botti, Alessandro Giunta, BOTTI, ELISABETTA, Alessandra Narcisi, Chimenti, Maria Sole, Perricone, Roberto, Paola Triggianese, Teoli, M, Narcisi, A, Miriam Teoli   +27 more
core   +1 more source

Inhibition of interleukins 17A and 17F in psoriatic arthritis [PDF]

, 2020
Psoriasis is the most common chronic inflammatory skin disease; 15–30% of patients with psoriasis have psoriatic arthritis.1 The interleukin (IL) 23 and IL17 pathway has a crucial role in pathogenesis, and inhibitors of the IL17 pathway have rewritten ...
Nash, P, Nash, Peter
core   +1 more source