Results 231 to 240 of about 77,580 (287)

Incidence rate and risk factors of arrhythmias in patients with psoriatic arthritis. [PDF]

RMD Open
Almansouri AY, Li J, Bumbulis L, Alhadari A, Colaco K, Harvey P, Akhtari S, Chandran V, Gladman DD, Cook RJ, Eder L.   +10 more
europepmc   +1 more source

Pharmacokinetic Model Selection for Personalized Infliximab Dosing in IBD

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.
ABSTRACT Infliximab, a monoclonal antibody used for immune‐mediated diseases, shows high interpatient pharmacokinetic variability. Prolonged exposure increases the risk of adverse effects and costs, making dose personalization essential to balance safety, efficacy, and cost‐effectiveness. Population pharmacokinetic models support individualized dosing,
Sahira Chaiben, Peggy Gandia, Thibaut Jamme, Nicolas Congy, Didier Concordet   +4 more
wiley   +1 more source

Systemic Treatment Strategies for Patients with Psoriasis and Psoriatic Arthritis in the Setting of ANA Positivity or Lupus Spectrum Disease: A Comprehensive Systematic Review. [PDF]

Int J Mol Sci
Tjiu JW, Tsai TF.
europepmc   +1 more source

Combined Maxacalcitol/Betamethasone Butyrate Propionate Ointment Possesses Long‐Term Sustained Effects of Inducing Regulatory T Cells and Downregulating the Th17 Response, Even After Discontinuation of Its Application in Imiquimod‐Induced Psoriasiform Dermatitis

The Journal of Dermatology, Volume 53, Issue 1, Page 25-34, January 2026.
ABSTRACT We often experience sustained improvement, even after discontinuation of treatment in psoriasis lesions treated with topical vitamin D3 (VD3) or the combination of topical corticosteroids and VD3. However, the underlying mechanisms of these sustained effects remain unclear. We explored mechanisms for the sustained effects of maxacalcitol (MCT)
Teruo Shimizu, Masahiro Kamata, Hideya Uratsuji, Yoshiki Okada, Ayu Watanabe, Azusa Hiura, Yayoi Tomura, Yayoi Tada   +7 more
wiley   +1 more source

Dual biologic therapy in a patient with severe psoriasis and psoriatic arthritis, using guselkumab and bimekizumab: A case report and review of the literature. [PDF]

SAGE Open Med Case Rep
Muylaert Barrett B, Music M, Yadav G.
europepmc   +1 more source

Deciphering Pigmented Rice Varieties as Sustainable and Unexplored Valuable Sources of Bioactive Components With Health‐Related Properties and Technological Applications—A Systematic Review

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT The interest in pigmented grains has grown substantially in recent years. Pigmented rice is crucial for diversifying agricultural production and promoting healthier, more balanced diets. This systematic review updates and discusses literature published between 2019 and 2024 on the bioactive compounds in pigmented rice, their potential health ...
Adolfo Pinheiro de Oliveira, Thatyane Mariano Rodrigues de Albuquerque, Evandro Leite de Souza   +2 more
wiley   +1 more source

Tocilizumab-induced psoriatic dermatitis in polyarticular juvenile idiopathic arthritis: A rare case report. [PDF]

SAGE Open Med Case Rep
Rajesh RY, Biju Seena P, Nakhutsrishvili E, Akkineni T, Ahmed AA, Suvvari TK, Thomas V, Singh T.   +7 more
europepmc   +1 more source

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Oral TYK2 Inhibitor D‐2570 in Healthy Subjects: A First‐in‐Human Phase I Study

Clinical and Translational Science, Volume 19, Issue 1, January 2026.
ABSTRACT D‐2570 selectively binds to the pseudokinase domain of tyrosine kinase 2, which mediates the downstream cytokine signaling pathways involved in immune regulation. The safety, tolerability, pharmacokinetics, and pharmacodynamics of D‐2570 were evaluated in a randomized, double‐blind, placebo‐controlled phase I study conducted in healthy Chinese
Meng Wang, Quanying Zhang, Zhe Shi, Ling Zhang, Jie Pan   +4 more
wiley   +1 more source

Psoriatic Arthritis Characteristics and Comorbidities in North Africa: Results of a Multicenter Retrospective Study. [PDF]

J Psoriasis Psoriatic Arthritis
Majjad A, El Guarti S, Mansouri H, Youssoufi T, Hassikou H, Efemba K, Harzy T, Fellous S, Allali F, Kabbou S, Ghozlani I, El Maghraoui A, Achemlal L.   +12 more
europepmc   +1 more source

A matter arising: When should inflammatory and autoimmune rheumatic diseases be considered ‘early’?

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Timely recognition of inflammatory and autoimmune rheumatic diseases (IARDs) is important to optimize the early diagnosis with tailored interventions and possible prevention of irreversible organ damage. This narrative review provides an update by summarizing the advances in identifying the early stages of rheumatoid arthritis, systemic sclerosis and ...
Elvis Hysa, Emanuele Gotelli, Carmen Pizzorni, Sabrina Paolino, Alberto Sulli, Vanessa Smith, Rosanna Campitiello, Maurizio Cutolo   +7 more
wiley   +1 more source