Results 241 to 250 of about 77,580 (287)

Reduced EZH2 Expression in Circulating CD8‐Positive T Cells and Monocytes in Psoriasis

open access: yesExperimental Dermatology, Volume 35, Issue 1, January 2026.
ABSTRACT Enhancer of Zeste Homologue 2 (EZH2) is an epigenetic regulator involved in immune cell differentiation and function; however, its role in psoriasis remains unknown. This study aimed to evaluate EZH2 expression in peripheral blood mononuclear cells from patients with psoriasis and explore its potential functional relevance to disease ...
Toyoki Yamamoto   +5 more
wiley   +1 more source

Outcomes in Bimekizumab Treated Psoriasis Patients With Prior IL-17 Inhibitor Failure. [PDF]

open access: yesJ Psoriasis Psoriatic Arthritis
Song EJ   +5 more
europepmc   +1 more source

What Is the Diagnostic Capacity of Existing Severity Scoring Tools for Nail Psoriasis?

open access: yesInternational Journal of Dermatology, Volume 65, Issue 1, Page 86-92, January 2026.
ABSTRACT Background It is challenging to distinguish nail psoriasis (NP) from nonspecific nail changes, contributing to heterogeneity in clinical trials. Existing scoring tools for NP are currently used to assess severity after diagnosis is established.
Evi C. C. Rikken   +5 more
wiley   +1 more source

Mitochondrial Activity Regulates Human T Helper 17 Differentiation and Function

open access: yesImmunology, Volume 177, Issue 1, Page 185-198, January 2026.
Naïve CD4+ T cells differentiating into RORγt+IL‐17A+ Th17 cells are characterised by a shift from glycolysis to oxidative phosphorylation. Early‐stage cells favour glycolysis, whereas later‐stage cells with hyperpolarised mitochondrial membrane potential (ΔΨ) rely more on oxidative phosphorylation, show increased activation, and differentiate more ...
Xinlai Chen   +10 more
wiley   +1 more source

Severe Delayed Hypersensitivity Reaction at Guselkumab Injection Site

open access: yes
Contact Dermatitis, Volume 94, Issue 1, Page 89-91, January 2026.
Salomé Allichon   +9 more
wiley   +1 more source

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