Results 31 to 40 of about 296,448 (281)

Psoriatic Arthritis and Diabetes: A Population-Based Cross-Sectional Study

Dermatology Research and Practice, 2013
Background. Diabetes has been associated with psoriasis, but little is known about the association between psoriatic arthritis and diabetes. Methods. Patients diagnosed with psoriatic arthritis by a rheumatologist were compared to age- and sex-matched ...
Jacob Dreiher, Tamar Freud, Arnon D. Cohen   +2 more
doaj   +1 more source

Assessing flares in patients with psoriatic arthritis using questionnaires

RMD Open
Objectives The psoriatic arthritis (PsA) FLARE Questionnaire was developed to study flares in PsA. We aimed to validate the FLARE Questionnaire and compare it with the Psoriatic Arthritis Impact of Disease 12-item Questionnaire (PsAID-12) to determine ...
Vinod Chandran, Daniel Pereira, Shangyi Gao, Nicholas J Chronis   +3 more
doaj   +1 more source

Persistence of biological agents over an eight-year period in rheumatoid arthritis and spondyloarthritis patients [PDF]

Farmacia Hospitalaria, 2019
Objective: To calculate the persistence, over a period of eight years, the retention rate of first and second-line of treatment with biological agents in patients with rheumatoid arthritis, spondyloarthritis and psoriatic arthritis and to compare ...
María Ángeles González-Fernández , Elena Villamañán , Inmaculada Jiménez-Nácher , Francisco Moreno , Alicia Herrero , Alejandro Balsa   +5 more
doaj   +1 more source

Challenges in the Metabolomics-Based Biomarker Validation Pipeline

Metabolites
As end-products of the intersection between the genome and environmental influences, metabolites represent a promising approach to the discovery of novel biomarkers for diseases.
Shenghan Li, Nikita Looby, Vinod Chandran, Vathany Kulasingam   +3 more
doaj   +1 more source

Identification of a Single Nucleotide Polymorphism in NFKBIA with Different Effects on Psoriatic Arthritis and Cutaneous Psoriasis in China

Acta Dermato-Venereologica, 2018
Genome-wide association studies have recently identified a number of non-major histocompatibility complex regions associated with psoriatic arthritis.
Qing Zhao, Yonghu Sun, Xi’an Fu, Zhenzhen Wang, Gongqi Yu, Zhenhua Yue, Yaru Wang, Huimin Zhang, Chuan Wang, Hong Liu, Qing Yang, Furen Zhang   +11 more
doaj   +1 more source

Identification of low-frequency TRAF3IP2 coding variants in psoriatic arthritis patients and functional characterization [PDF]

, 2012
Introduction: In recent genome-wide association studies for psoriatic arthritis (PsA) and psoriasis vulgaris, common coding variants in the TRAF3IP2 gene were identified to contribute to susceptibility to both disease entities.
Maria Apel, Böhm, Beate B., Steffen Uebe, Böhm, Beate, Apel, Maria, Behrens, Frank, Harald Burkhardt, Frank Behrens, Burkhardt, Harald, Beate Bohm, Hüffmeier, Ulrike, Ulrike Huffmeier, Reis, André, Uebe, Steffen, Andre Reis   +14 more
core   +1 more source

Chronic kidney disease in patients with psoriatic arthritis: a cohort study

RMD Open
Objectives Chronic kidney disease (CKD) is a comorbidity in psoriatic arthritis (PsA). We aimed to define the prevalence of CKD in patients with PsA, describe their long-term renal outcomes and identify risk factors for CKD development.Methods We ...
Dafna D Gladman, Vinod Chandran, Richard J Cook, Fadi Kharouf, Shangyi Gao, Shahad Al-Matar   +5 more
doaj   +1 more source

ENTHESITIS AND PSORIATIC ONYCHOPATHY AS A FACTOR FOR PREDICTION OF PSORIATIC ARTHRITIS IN PSORIASIS

Vestnik Dermatologii i Venerologii, 2018
Psoriatic arthritis is a psoriasis-related spondyloarthropathy that occurs in 20–30 % of patients with psoriasis. Psoriatic arthritis affects the patient’s quality of life indicators and are more often associated with disabilities of working age than ...
Tatyana G. Sidorcika, Viktor A. Linovs, Maya A. Radzina, Andris J. Rubins, Sylvester A. Rubins   +4 more
doaj   +1 more source

Discordance Between Patient and Physician Global Assessments in Early Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective This study aims to identify factors associated with patient global assessment (PtGA) and physician global assessment (PhGA) and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (<5 years) from the Collaborative National Quality and Efficacy Registry were included.
Ellen Romich, Alexis Ogdie, Alisa Stephens Shields, Peter A. Merkel, Shervin Assassi, Elana J. Bernstein, Andreea Bujor, Flavia V. Castelino, Lorinda Chung, Luke B. Evnin, Tracy M. Frech, Jessica K. Gordon, Melissa Griffith, Faye N. Hant, Monica L. Harding, Laura K. Hummers, Dinesh Khanna, Kimberly S. Lakin, Dorota J. Lebiedz‐Odrobina, Yiming Luo, Ashima Makol, Maureen D. Mayes, Zsuzsanna H. McMahan, Jerry Molitor, Duncan F. Moore, Julie Paik, Carrie Richardson, Brian Skaug, Ami A. Shah, Ankoor Shah, Virginia Steen, John M. VanBuren, Elizabeth R. Volkmann, Carleigh Zahn, Nora Sandorfi, for the CONQUER Investigators   +35 more
wiley   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

Angewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma, Komal Sharma, Anku Sharma, Kamya Rao, Rahul Jain, Brett VanVeller   +5 more
wiley   +2 more sources