Results 241 to 250 of about 621,634 (301)

Retraction: Extraction of anthocyanins from purple sweet potato: evaluation of anti-inflammatory effects in a rheumatoid arthritis animal model, mechanistic studies on inflammatory cells, and development of exosome-based delivery for enhanced targeting. [PDF]

Front Immunol
Frontiers Editorial Office.
europepmc   +1 more source

Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
Yaqiang Hu et al. engineered a pathogenic Sec16a mutant mouse model using CRISPR/Cas9 technology. They observed that the Sec16a mutant mice displayed diminished learning and memory capabilities, along with a limb‐clasping phenotype upon tail suspension.
Yaqiang Hu, Zhiyang Zeng, Xinyu Ming, Shuming Yin, Yuting Guan, Liangcai Gao, Dali Li   +6 more
wiley   +1 more source

Association between autoimmune thyroiditis and rheumatoid arthritis: a cross-sectional risk stratification study. [PDF]

Front Endocrinol (Lausanne)
Ji X, Zhang Y, Zhang S, Shao S, Wu J.
europepmc   +1 more source

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Cavitary Pulmonary Nodules Associated With Leflunomide Therapy in Rheumatoid Arthritis: A Case Report and Literature Review. [PDF]

Cureus
Bedak D, Sejdinovic R, Prnjavorac B, Hakic-Beslagic H, Ibrahimovic A, Mahmutovic A, Bedak O.   +6 more
europepmc   +1 more source

The characteristics of collagen‐induced rheumatoid arthritis in macaques and the changes of heart

Animal Models and Experimental Medicine, EarlyView.
The disease progression in CIA macaques was categorized into three stages: IIR (days 14–34): The indicators related to rheumatoid arthritis and the levels of immunoglobulin were all elevated. There was a small amount of joint effusion, edema and mild synovial hyperplasia. No joint swelling was observed by naked eye.
Lei Zhang, Haifeng Jiang, Zhen Xu, Tingyu Dong, Xiaoyi Liu, Shangxue Yan, Jiajie Kuai, Yan Chang, Wei Wei   +8 more
wiley   +1 more source

Birth length and perinatal exposures and rheumatoid arthritis risk in the E3N cohort. [PDF]

RMD Open
Dusser P, Nguyen Y, Perrin C, Frénoy P, Mariette X, Boutron-Ruault MC, Severi G, Salliaot C, Seror R.   +8 more
europepmc   +1 more source

Genetic prediction of blood cell reactivity and its potential causal influence on bone continuity and density disorders

Animal Models and Experimental Medicine, EarlyView.
We applied Mendelian randomization to explore causal links between blood cell traits and skeletal disorders. Using genetic instruments from large‐scale summary statistics, we assessed effects on bone continuity, density, and structural integrity. Sensitivity and reverse analyses confirmed robust associations, highlighting potential shared biological ...
Zhiqin Deng, Zhe Zhao, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Zhengyang Lin, Zhenhan Deng, Wencui Li   +8 more
wiley   +1 more source

Effect of Anti-Cyclic Citrullinated Peptide Antibody Serostatus on Outcomes of Silicone Metacarpophalangeal Arthroplasty in Patients With Rheumatoid Arthritis. [PDF]

Hand (N Y)
Schluttenhofer A, Postal Z, Bankes A, Schaffer D, Rizzo M.   +4 more
europepmc   +1 more source