Results 51 to 60 of about 62,506 (257)

A systematic review of the evidence for single stage and two stage revision of infected knee replacement [PDF]

open access: yes, 2013
BACKGROUND: Periprosthetic infection about the knee is a devastating complication that may affect between 1% and 5% of knee replacement. With over 79 000 knee replacements being implanted each year in the UK, periprosthetic infection (PJI) is set to ...
A Beswick   +94 more
core   +1 more source

Editorial Commentary: Early Changes, Lasting Gains: Ten‐Year Outcomes After Hip Arthroscopy For Tönnis 0 and 1

open access: yesArthroscopy, EarlyView.
Abstract After more than a decade performing hip arthroscopy for femoroacetabular impingement syndrome, I have seen how long‐term evidence continues to validate what early clinical experience suggested—that hip arthroscopy provides durable, meaningful, and reproducible outcomes when applied with sound judgment.
David R. Maldonado
wiley   +1 more source

Infection burden in total hip and knee arthroplasties: an international registry-based perspective

open access: yesArthroplasty Today, 2017
Background: Infection remains a leading cause of failure of hip and knee replacements. Infection burden is the ratio of implants revised for infection to the total number of arthroplasties in a specific period, measuring the steady state of infection in ...
Bryan D. Springer, MD   +4 more
doaj   +1 more source

Conventional versus highly cross-linked polyethylene in primary total knee replacement : a comparison of revision rates using data from the National Joint Registry for England, Wales, and Northern Ireland [PDF]

open access: yes, 2020
There is evidence to support the use of highly cross-linked polyethylene (HXLPE) in patients undergoing total hip arthroplasty. However, the benefits for those undergoing total knee arthroplasty are uncertain, with conflicting reports based on previous ...
Baker, Paul N.   +5 more
core   +1 more source

Visual Hypersensitivity as a Transdiagnostic Marker of Surgical Pain Response in Arthritis and Chronic Pain Syndromes

open access: yesArthritis &Rheumatology, EarlyView.
Objective Nociplastic pain is pain primarily driven by the central nervous system and, unlike nociceptive pain conditions, is thought to be refractory to peripherally directed therapies. Nociplastic pain is also associated with hypersensitivity to painful and other sensory stimuli (such as visual stimuli). Nonpainful sensory measures have not been well
Noah Waller   +15 more
wiley   +1 more source

Effect of oxycodone vs. morphine as first‐line opioid on new persistent opioid use after orthopaedic surgery: A prospective sequential cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Background Postoperative opioids, intended for short‐term analgesia, contribute to new persistent opioid use in 1%–7% of patients, adversely affecting outcomes. Oxycodone may carry higher risk than morphine, though long‐term data are limited.
Eward J. Melis   +5 more
wiley   +1 more source

Early Development of Total Hip Replacement [PDF]

open access: yes, 2007
Annotated and edited transcript of a Witness Seminar held on 14 March 2006. Introduction by Dr Francis Neary and Professor John Pickstone. First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2007. ©The Trustee of the Wellcome
Reynolds, LA, Tansey, EM
core  

Tranexamic Acid in Lower Extremity Endoprosthetic Reconstruction for Oncologic Indications: A Retrospective Comparative Study of 617 Patients

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives While tranexamic acid (TXA) reduces blood loss in orthopedic surgery, thromboembolic concerns in cancer patients have limited adoption in orthopedic oncology. This study evaluated TXA efficacy and safety in patients undergoing endoprosthetic reconstruction for oncologic indications.
Stephen W. Chenard   +10 more
wiley   +1 more source

A new mini-navigation tool allows accurate component placement during anterior total hip arthroplasty. [PDF]

open access: yes, 2018
Introduction: Computer-assisted navigation systems have been explored in total hip arthroplasty (THA) to improve component positioning. While these systems traditionally rely on anterior pelvic plane registration, variances in soft tissue thickness ...
Benson, Jessica R.   +2 more
core   +1 more source

Valproic Acid Inhibits Ferroptosis and Improves Bone Integration in OVX Rats Through the AMPK/SIRT1 Pathway

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The prevalence of postmenopausal osteoporosis (PMOP) has been steadily increasing. Ferroptosis has been recognized as a critical factor influencing the bone‐forming ability of bone marrow mesenchymal stem cells (BMSCs). Valproic acid (VPA), an HDAC inhibitor, has been suggested to play a role in regulating osteoporosis development; however ...
Qing‐Song Gu   +8 more
wiley   +1 more source

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