Results 61 to 70 of about 198,308 (296)

Dose optimization in surgical prophylaxis: sub-inhibitory dosing of vancomycin increases rates of biofilm formation and the rates of surgical site infection

Scientific Reports, 2023
Antibiotic stewardship is viewed as having great public health benefit with limited direct benefit to the patient at the time of administration. The objective of our study was to determine if inappropriate administration of antibiotics could create ...
Kimberly M. Brothers, Dana M. Parker, Masashi Taguchi, Dongzhu Ma, Jonathan B. Mandell, Lance L. Thurlow, Venkata C. Byrapogu, Kenneth L. Urish   +7 more
doaj   +1 more source

Advanced Testing Protocols Simulate Failures and Validate Antioxidant Polyethylene in Ankle Implants

Journal of Orthopaedic Research, EarlyView.
Abstract Total ankle replacement (TAR) has become an effective treatment for end‐stage ankle osteoarthritis. Multiple factors, including patient characteristics, surgical technique, alignment, and bearing surfaces, influence TAR survivorship. Polyethylene (PE) fatigue is a key consideration in improving outcomes.
Ryan Siskey, Patrick Hall, Ruth Heckler, David Safranski, James Johnson, Ariel Palanca   +5 more
wiley   +1 more source

Comparison of External Rotation Torque of Short External Rotator Muscles in Hip Flexion Position

Journal of Orthopaedic Research, EarlyView.
Preserving the short external rotator muscles of the hip helps prevent dislocation after total hip arthroplasty, but it's unclear which muscles are most critical. This study quantified the external rotation torque in cadaveric hips and found that the obturator externus provides the highest torque during deep hip flexion, where dislocations often occur.
Yoshiaki Ito, Daisuke Suzuki, Fumiya Kizawa, Arata Kanaizumi, Toshihito Hiraiwa, Takashi Tamura, Yoshiharu Kawaguchi, Satoshi Nagoya   +7 more
wiley   +1 more source

Reduced Muscle Strength Can Alter the Impact of Gait Modifications on Knee Cartilage Mechanics

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Muscle strength can substantially influence knee joint loading, stability, and cartilage biomechanics, all of which are important factors in the onset and progression of knee osteoarthritis (KOA). Noninvasive rehabilitation methods, such as gait modifications, are suggested to effectively alter knee joint loading, potentially helping to ...
Joose P. J. Peitola, Amir Esrafilian, Morten B. Simonsen, Michael S. Andersen, Rami K. Korhonen   +4 more
wiley   +1 more source

Evaluation of the Baseplate Position and Screws in Reverse Total Shoulder Arthroplasty Using 3D Printed Patient‐Specific Instrumentation

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Patient‐specific instrumentation (PSI) in shoulder arthroplasty has been used to translate preoperative surgical planning into precise implant positioning. However, screws for baseplate fixation using PSI have not been preoperatively planned or verified for proper location and length.
Wonhee Lee, Woojin Yu, HwaYong Lee, Guk Bae Kim, In‐Ho Jeon, Kyoung Hwan Koh   +5 more
wiley   +1 more source

Primary constrained and hinged total knee arthroplasty: 2- and 5-year revision risk compared with unconstrained total knee arthroplasty: a report on 401 cases from the Norwegian Arthroplasty Register 1994–2017

Acta Orthopaedica, 2019
Background and purpose — The number of primary, highly constrained knee arthroplasty implants has increased with a theoretically increased risk of early failure.
Mona Badawy, Anne Marie Fenstad, Ove Furnes   +2 more
doaj   +1 more source

Low revision rate of dual mobility cups after arthroplasty for acute hip fractures: report of 11,857 hip fractures in the Dutch Arthroplasty Register (2007–2019)

Acta Orthopaedica, 2020
Background and purpose — Dislocation is one of the most frequent reasons for cup revision after total hip arthroplasty (THA) for an acute fracture. A dual mobility cup (DMC) might reduce this risk.
Esther M Bloemheuvel, Liza N Van Steenbergen, Bart A Swierstra   +2 more
doaj   +1 more source

A Machine Learning Approach to Microcalorimetric Pattern Classification of Pathogens in Synovial Fluid

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Isothermal microcalorimetry (IMC) is a promising tool for diagnosing periprosthetic joint infection (PJI), based on real‐time measurement of growth‐related heat production of pathogens, and faster than conventional microbial cultures. However, the feasibility of identifying specific pathogens in clinical samples using IMC has yet to be proven.
Manuel Lozano‐García, Luis Estrada‐Petrocelli, Roger Rosselló Román, Raimon Jané, Andrej Trampuz, Christian Morgenstern   +5 more
wiley   +1 more source

Lower 5-year cup re-revision rate for dual mobility cups compared with unipolar cups: report of 15,922 cup revision cases in the Dutch Arthroplasty Register (2007–2016)

Acta Orthopaedica, 2019
Background and purpose — During revision hip arthroplasty the dual mobility cup (DMC) is widely used to prevent dislocation despite limited knowledge of implant longevity. We determined the 5-year cup re-revision rates of DMC compared with unipolar cups (
Esther M Bloemheuvel, Liza N van Steenbergen, Bart A Swierstra   +2 more
doaj   +1 more source

Anemia, Abnormal Body Mass Index, and Sarcopenia Increase Complication Risk in Patients Undergoing Surgical Treatment for Metastatic Bone Disease

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Metastatic bone disease (MBD) is a common complication of primary cancers and is typically managed surgically. Overall health status and nutritional optimization are essential in surgical outcomes. The objective of this study was to report the intersectionality of previously studied laboratory, imaging, and clinical ...
Joseph Ippolito, Ashley Castan, Rosamaria Dias, Yazan Kadkoy, Katie Gotoff, Jennifer Thomson, Kathleen Beebe, Joseph Benevenia   +7 more
wiley   +1 more source