Results 131 to 140 of about 50,293,051 (325)

Justifying No-Better Than Never [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Rashmi Patnayak, Amitabh Jena
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Four Flats News Article

open access: yes, 1952
An issue of The Ship\u27s Log of the Marine Medical Mission, Inc featuring an article on the Four Flats.https://digitalcommons.georgefox.edu/fourflats_papers/1050/thumbnail ...
George Fox University Archives
core  

Mastering the Art of First Impressions: Tips to Write a Title, Abstract, and Keywords for a Medical Manuscript

open access: yesIndian Journal of Radiology and Imaging
Formulating the title and abstract of a manuscript is crucial to convey the essence of the research paper to the reader at a superficial glance. The title should be short and crisp, yet it should define critical information about the paper, such as the ...
Kurian C. Eapen   +2 more
doaj   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

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