Results 131 to 140 of about 57,433,167 (306)
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The process of harnessing solar power through the Ashwamedha Yagya.
The first Ashwamedha Yagya under the Dev Sanskriti Digvijay Abhiyan of the All World Gayatri Family took place in Jaipur, Rajasthan from November 7th to 10th, 1992.
Reprint
doaj +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Політична теологія «руского міра»: теоретичні витоки та академічна інституалізація
У статті проаналізовано витоки концепції «руского міра» з теоретичних розробок слов’янофілів. Слов’янофільство у своїх основних тезах ніколи не зникало з історіософського дискурсу Росії, лише адаптувалося під актуальний політичний контекст.
Руслана Демчук
doaj +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Analysis on forwards writing of articles papers published in nursing periodicals
Objective :topromo tethew rit ingqualityof forwa rdsofpa persi nnursingp eri odicals.Met hod :atotalof 5mag azinesw hichcanre present allnursing perio dicalswe reselected ,thenrea dtheforwards ofpapersone byone ,toknowabout“researc hhistoriesd onebypio
王菊香
doaj

