Results 161 to 170 of about 50,293,051 (325)
Contribution à l'étude des Saxifrages du groupe desDactyloidesTausch (24eArticle) [PDF]
M. D. Luizet
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Determinarea – o problematică a limbii române contemporane [PDF]
Through this article, we propose a synthesis of the main studies on determination in Romanian language, revealing the convergent or divergent perspectives adopted by the authors.
Cipriana-Elena ÇAVAȘ
doaj
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
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THE PRESENT STATUS OF ANTHROPOLOGY IN NORTHEASTERN NORTH AMERICA; A REVIEW ARTICLE [PDF]
William N. Fenton
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The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
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The Vitamin B ComplexThis article was written in May 1940. [PDF]
H. M. Sinclair
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Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
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The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
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