Results 241 to 250 of about 48,303,877 (349)
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini+10 more
wiley +1 more source
Digital Long Covid Communities-Shaping Diagnoses, Treatment Strategies and Modes of Expertise. [PDF]
Almqvist-Ingersoll P.
europepmc +1 more source
ARTICLE II. Ox SIMULTANEOUS LIGATION OF THE COMMON CAROTID AND OF THE SUBCLAVIAN IN ITS THIRD PORTION IN THE TREATMENT OF SUPPOSED ANEU-RISM OF THE ARTERIAL INNOMINATA, WITH A CASE [PDF]
Lewis A. Stimson
openalex +1 more source
The roles and applications of extracellular vesicles in cancer
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley +1 more source
Plasma Trough Concentrations of Beta-Lactam Antibiotics in the Early Phase of Septic Shock. [PDF]
Hägglund M+4 more
europepmc +1 more source
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan+10 more
wiley +1 more source
Transforming Patient-Reported Outcome Measurement With Digital Health Technology. [PDF]
Jackman L, Kamran R.
europepmc +1 more source