Results 241 to 250 of about 21,153,807 (271)

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Reviewed article: Souza IG, Duarte YAO, Nascimento MMG, Molino CGRC, Rezende CP, Santos JLF. Competições terapêuticas e fragilidade em pessoas idosas no município de São Paulo: estudo transversal de base populacional, 2015. Epidemiol Serv Saude. 2025:34;20240104. 10.1590/S2237-96222025v34e20240104.en. [PDF]

Epidemiol Serv Saude
Almada Filho CM.
europepmc   +2 more sources

Proportion of parental genomes in hybrids Allium cepa × A. roylei determines which one becomes dominant. [PDF]

Plant Genome
Kopecký D, Duchoslav M, Scholten O, Kneřová J, Szecówka M.   +4 more
europepmc   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Retraction: Impact of the hydraulic fracturing on indoor radon concentrations in Ohio: a multilevel modeling approach. [PDF]

Front Public Health
Frontiers Editorial Office.
europepmc   +1 more source

Retraction Note: Machine learning intelligent based hydromagnetic thermal transport under Soret and Dufour effects in convergent/divergent channels: a hybrid evolutionary numerical algorithm. [PDF]

Sci Rep
Aslam MN, Shaukat N, Riaz A, Khan I, Niazai S.   +4 more
europepmc   +1 more source

Reviewed article: Siqueira PC, Sales CMM, Prado TN, Maciel ELN. Análise da completude das fichas de notificação de covid-19 na população indígena no Espírito Santo, 2020. Epidemiol Serv Saude. 2025:34;20240176. [PDF]

Epidemiol Serv Saude
Sá ACMGN.
europepmc   +1 more source

Correction: Comprehensive techno-environmental evaluation of an isolated PV/wind/biomass hybrid microgrid employing various battery technologies: A comparative analysis. [PDF]

PLoS One
PLOS One Staff.
europepmc   +1 more source

Correction: Human intracardiac SSEA4+CD34- cells show features of cycling, immature cardiomyocytes and are distinct from Side Population and C-kit+CD45- cells. [PDF]

PLoS One
PLOS One Staff.
europepmc   +1 more source

CD44v, S1PR1, HER3, MET and cancer‐associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb

FEBS Open Bio, EarlyView.
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano, Kouki Okita, Shogo Okazaki, Soshi Yoshimoto, Sachiko Masuko, Hideki Yagi, Kazunori Kato, Yoshihisa Tomioka, Kenichi Imai, Yoichi Hamada, Kazue Masuko, Kayoko Shimada‐Takaura, Noriaki Nagai, Hideyuki Saya, Tomio Arai, Toshiyuki Ishiwata, Takashi Masuko   +16 more
wiley   +1 more source