Results 91 to 100 of about 14,377,049 (345)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

On Growth, Disorder, and Field Theory

, 1998
This article reviews recent developments in statistical field theory far from equilibrium. It focuses on the Kardar-Parisi-Zhang equation of stochastic surface growth and its mathematical relatives, namely the stochastic Burgers equation in fluid ...
Ala-Nissila T, Balents L, Bausch R, Cardy J L, Chekhlov A, Cook J, Cook J, de Gennes P G, Drasdo D, Drasdo D, Evans M R, Forgacs G, Hwa T, Hwa T, Hwa T, Imbrie J Z, Itzykson C, Kim J M, Kinzelbach H, Kolmogorov A, Krug J, Krug J, Lipowsky R, Lässig M, Lässig M, Lässig M, Lässig M, Maunuksela J, Meakin P, Michael Lässig, Mukherji S, Mézard M, Mézard M, Nattermann T, Nattermann T, Olsen R, Rajasekaran J J, Tang L-H, van Dijken S, Wiese K J, Willbrand K, Wolf D, Zhang Y-C   +42 more
core   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Brexit Transitional Period: The solution is Article 50. CEPS Commentary, 9 September 2017 [PDF]

, 2017
As the Brexit negotiations labour on, the complexity of what lies ahead is finally, painfully, becoming clear to the UK government. Some Brexiteers, including Secretary of State for Exiting the European Union, David Davis, now seem to accept the idea ...
Frantziou , Eleni, Łazowski , Adam
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Motivational interest of women of 30-50 years old to the studying of healthy exercises [PDF]

Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2011
This article shows the actual problem, which is not so frequently in the publications of scientific-methodical literature, namely, the identification of motivations to attend to fitness physical exercises women of 30-50 years old.
Sorokina S.O., Kudryashova T.I.
doaj  

Psychological and organisational aspects of age management in organisations

Management, 2017
In article we present selected issues of age management in organizations. They pointed to the lack of rationale for the discriminatory policies of some companies to employees aged 50+.
Witkowski Stanisław A., Bartosz Bogna
doaj   +1 more source

Article 50. Deferment of publication

, 2020
openaire   +2 more sources

Temperature-dependent Fermi surface evolution in heavy fermion CeIrIn5

, 2011
In Cerium-based heavy electron materials, the 4f electron's magnetic moments bind to the itinerant quasiparticles to form composite heavy quasiparticles at low temperature.
B. I. Min, G. Kotliar, Hong Chul Choi, J. H. Shim, K. Haule, R. D. Cowan   +5 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source