Results 101 to 110 of about 14,377,049 (345)

NEW METHOD OF PERSONIFIED EVALUATION OF RISK OF CARDIOVASCULAR DISEASES BY THE COEFFICIENT OF ATHEROGENICITY

open access: yesАтеросклероз, 2017
The aim of the work is to develop a new atherogenic coefficient as a personalized method for assessing cardiovascular risk in patients with dyslipidemia. Materials and methods. The subject of the study was a sample of men and women ( n = 100 people) with
L. D. Latyntseva   +3 more
doaj  

Parliament’s role in the Brexit negotiations: Article 50 and beyond [PDF]

open access: yes, 2016
If the recent high court ruling on Brexit is upheld, then MPs in the UK Parliament will have to approve the decision to trigger Article 50 and begin the process for leaving the European Union.
Hagemann, Sara
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

SUSY vertex algebras and supercurves

open access: yes, 2006
This article is a continuation of math.QA/0603633 Given a strongly conformal SUSY vertex algebra V and a supercurve X we construct a vector bundle V_X on X, the fiber of which, is isomorphic to V. Moreover, the state-field correspondence of V canonically
A. Beilinson   +25 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Treatment of Myofascial Trigger Points of Pelvic Floor with Physiotherapeutic Package: A Case Report

open access: yesJournal of Rehabilitation Sciences and Research, 2015
Background: There are various factors that may cause pain and dysfunction in the pelvic region. Myofascial trigger points can likewise contribute in pelvic pain.
Esmaeil Shokri   +2 more
doaj  

Brexit and Acquired Rights

open access: yesAJIL Unbound, 2017
On March 29, 2017, the U.K. Government triggered Article 50 of the Treaty on European Union (TEU) on withdrawal from the European Union following a referendum on June 23, 2016 in which 51.89 percent voted for the United Kingdom to leave the European ...
Michael Waibel
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Cultural Studies und kritische Pädagogik

open access: yesMedienPädagogik: Zeitschrift für Theorie und Praxis der Medienbildung, 2004
Der Autor stellt die Cultural Studies als transdisziplinäre Forschungsrichtung vor, die in den 50er Jahren in Großbritannien begründet wurde. Diese orientieren sich an alltäglichen Lebenswelten, "Kultur" bezeichnet ein Netzwerk von gesellschaftlichen ...
Rainer Winter
doaj   +1 more source

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