Results 261 to 270 of about 14,377,049 (345)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

The Benefits Outweigh the Costs: Illinois Should Apply State Exclusionary Rule as Remedy for Article I Section 6 Violations, 50 J. Marshall L. Rev. 397 (2017)

, 2017
Nicholas J. Kamide
openalex   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

"Incredibly Overwhelming": A Reflexive Thematic Analysis of the Psychological Impact of Venous Thromboembolism-A Patient-Oriented Study. [PDF]

J Patient Exp
Carrillo-Balam G, Lee T, Rajanderan T, Mackenzie T, Bonsu KO, Young S.   +5 more
europepmc   +1 more source

Impact of Lipid Composition on Membrane Partitioning and Permeability of Gas Molecules. [PDF]

Membranes (Basel)
Mahinthichaichan P, Raeisi Najafi A, Moss FJ, Vahedi-Faridi A, Boron WF, Tajkhorshid E.   +5 more
europepmc   +1 more source

The Joint Commission Journal on Quality and Patient Safety 50th Anniversary Article Collections: 50 Most Cited

openalex   +1 more source