Results 71 to 80 of about 14,377,049 (345)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Ultra-portable explosives sensor based on a CMOS fluorescence lifetime analysis micro-system [PDF]
, 2011 The paper published in AIP Advances (a new journal from the American Institute of Physics) had 1100 article downloads in the first 5 months after publication, and was on the journal’s “most read” list for 4 months.
Dawson, Martin D. +8 more
core +2 more sources
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Microsurgery: The Top 50 Classic Papers in Plastic Surgery: A Citation Analysis
Archives of Plastic Surgery, 2014 Background The number of citations that a published article has received reflects the importance of the paper in the particular area of practice. In microsurgery, thus far, which journal articles are cited most frequently is unknown. The purpose of this
Cormac Weekes Joyce +1 more
doaj +1 more source
The major changes in medical practice in the 20th century [PDF]
, 2000 One could truly say that there were more advances in medicine in the last 60 years than there had been in the previous 500 years. Indeed the medical breakthroughs of the last 50 years have probably saved more lives than those of any epoch since medicine ...
Fenech, Frederick F.
core
An unfolding signifier: London's Baltic Exchange in Tallinn [PDF]
, 2008 In the summer of 2007 an unusual cargo arrived at Muuga and Paldiski harbors outside Tallinn. It consisted of nearly 50 containers holding over 1,000 tons of building material ranging from marble columns, staircases and fireplaces, to sculpted ...
Alas J +32 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
From the history of the Department of Mathematics at the Agricultural University of Lithuania
Lietuvos Matematikos Rinkinys, 1999 The article is dedicated to the 50 years anniversary of the Mathematics Department. The foundation's history is described there. All the heads of the Department and their biographies are mentioned in this article.
Janina Kaminskienė, Janina Liubertienė
doaj +3 more sources
The seven days of Brexit: how a Leave government could bypass Article 50 [PDF]
, 2016 Most agree that leaving the EU would entail a negotiating period of at least two years, as set out in Article 50 of the Treaty on European Union. But, argue Frank Vibert and Gunnar Beck, this is not a certainty. If a Brexit vote – combined with a Commons
Beck, Gunnar, Vibert, Frank
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source