Results 81 to 90 of about 4,144,457 (271)

Ranking Archived Documents for Structured Queries on Semantic Layers

open access: yes, 2018
Archived collections of documents (like newspaper and web archives) serve as important information sources in a variety of disciplines, including Digital Humanities, Historical Science, and Journalism.
Arikan Irem   +8 more
core   +1 more source

Interactivity in professional online learning: A review of research based studies [PDF]

open access: yes, 2007
Over the last few years, the higher education and the vocational education and training sectors have increased the number of online learning courses available for professionals.
Maor, D., Volet, S.
core   +3 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Assessment of genetically modified maize MON 87460 for renewal authorisation under Regulation (EC) No 1829/2003 (dossier GMFF‐2023‐21251)

open access: yesEFSA Journal
Following the submission of dossier GMFF‐2023‐21251 under Regulation (EC) No 1829/2003 from Bayer CropScience LP, the Panel on Genetically Modified Organisms of the European Food Safety Authority was asked to deliver a scientific risk assessment on the ...
EFSA Panel on Genetically Modified Organisms (GMO)   +21 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Weighted Spectral Embedding of Graphs [PDF]

open access: yes, 2018
We present a novel spectral embedding of graphs that incorporates weights assigned to the nodes, quantifying their relative importance. This spectral embedding is based on the first eigenvectors of some properly normalized version of the Laplacian.
Bonald, Thomas   +2 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Profiling research published in the journal of enterprise information management (JEIM) [PDF]

open access: yes, 2010
Purpose – The purpose of this paper is to analyse research published in the Journal of Enterprise Information Management (JEIM) in the last ten years (1999 to 2008).
Dwivedi, YK, Mustafee, N
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Bedside differentiation of vestibular neuritis from central "vestibular pseudoneuritis". [PDF]

open access: yes, 2008
Acute unilateral peripheral and central vestibular lesions can cause similar signs and symptoms, but they require different diagnostics and management.
Brandt, Thomas   +4 more
core   +1 more source

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