Results 31 to 40 of about 370,024 (214)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Evaluation of correlation between cephalometric variables and internal derangement of temporomandibular joint in asymptomatic class II division I high angle patients using Helical computed tomography

SRM Journal of Research in Dental Sciences, 2013
Introduction: The aim of this study was to identify the presence of articular disk displacement using helical computed tomography (CT) in asymptomatic Class II Division I patients and to find a correlation between internal derangement of ...
Diravidamani Kamatchi, Vasanthan Palanivel, Sathesh Kumar Sivalingam   +2 more
doaj   +1 more source

Absorbance or organization into ankylosis: a microarray analysis of haemarthrosis in a sheep model of temporomandibular joint trauma

BMC Oral Health, 2021
Background Traumatic haemarthrosis was hypothesized to be the etiology of temporomandibular (TMJ) ankylosis. Here, taking haematoma absorbance as a control, we aimed to reveal the molecular mechanisms involved in haematoma organizing into ankylosis using
Mai-Ning Jiao, Tong-Mei Zhang, Kun Yang, Zhao-Yuan Xu, Guan-Meng Zhang, Yuan-Yuan Tian, Hao Liu, Ying-Bin Yan   +7 more
doaj   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

A prospective study of 138 arthroscopies of the temporomandibular joint

Brazilian Journal of Otorhinolaryngology, 2015
INTRODUCTION: Internal derangements (ID) of the temporomandibular joint (TMJ) have a multifactorial etiology and are most often treated conservatively by splints, physical therapy and medications.
Paulo Alexandre da Silva, Maria Teresa de Fatima Fernandes Lopes, Fernando Silva Freire   +2 more
doaj   +1 more source

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source

Aging Changes in the Articular Disk of the Temporomandibular Joint in the Guinea Pig

, 1976
The development of cartilage cells was investigated in the articular disks of the temporomandibular joint (TMJ disk) from two groups of guinea pigs age 1 month and 2 years old.
Anastasios Tsaknakis, Demetrius Karakasis   +1 more
core   +1 more source

Cartilage tissue engineering using pre-aggregated human articular chondrocytes [PDF]

, 2008
In this study, we first aimed at determining whether human articular chondrocytes (HAC) proliferate in aggregates in the presence of strong chondrocyte mitogens.
Farhadi, J., J Farhadi, M Heberer, C Candrian, D Wendt, Wendt, D., A Barbero, Barbero, A., F Wolf, Wolf, F., Martin, I., Candrian, C., Heberer, M., I Martin, Wendt D, Heberer M, Barbero A, Candrian C, Farhadi J, Martin I, Wolf F   +20 more
core   +2 more sources

Multi‐Tissue Crosstalk Regulating Meniscus Healing Under Inflammation and Physiological Loading

Advanced Science, EarlyView.
Using a novel Meniscus‐on‐a‐chip (MoC) model integrated with a meniscus‐specific bioreactor, this study investigated the roles of multi‐tissue crosstalk that regulates injury, healing, and degeneration of the meniscus injury under inflammation and pathophysiological loading.
Hun Jin Jeong, Elen Zhu, Min Seo Kang, Ming Wang, Sam Comito, Chang H. Lee   +5 more
wiley   +1 more source

Condylar osteochondroma: Report of a case with literature review

SRM Journal of Research in Dental Sciences, 2013
Osteochondroma is one of the most common benign tumors of the skeleton, but osteochondroma of the mandibular condyle is relatively rare and may cause signs and symptoms similar to those seen in patients with temporomandibular joint (TMJ) dysfunction ...
Anita Singhal, Ramesh Venkatpathy, Parul Singhal   +2 more
doaj   +1 more source