Results 71 to 80 of about 53,685 (249)

Efeitos hemodinâmicos e metabólicos da movimentação passiva dos membros inferiores em pacientes sob ventilação mecânica Hemodynamic and metabolic effects of passive leg movement in mechanically ventilated patients

Revista Brasileira de Terapia Intensiva, 2010
OBJETIVO: A movimentação passiva dos membros executada por um fisioterapeuta demonstrou resultar em aumentos significantes nas variáveis metabólicas e hemodinâmicas em pacientes criticamente enfermos. O objetivo deste estudo foi determinar se o movimento
Augusto Savi, Cristiano Pires Maia, Alexandre Simões Dias, Cassiano Teixeira   +3 more
doaj   +1 more source

ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief

Advanced Science, EarlyView.
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng, Changyu Liu, Qin Xia, Arndt F. Schilling, Jiawei Jiang, Renpeng Peng, Zixing Shu, Tian Ma, Danni Luo, Yaoyu Zhang, Yibo Fan, Xuyuan Zhang, Song Li, Kai Wang, Wentao Ke, Yuan Xiong, Yuanli Zhu, Fangzhi Mou, Jun Xiao, Hao Zhu   +19 more
wiley   +1 more source

Clothing interference in performance, articular range of motion and comfort in labor gymnastics

Revista Brasileira de Cineantropometria e Desempenho Humano, 2010
The objective of this descriptive case study was to analyze the interference of clothing with exercise performance, joint range of motion (ROM), and comfort during a session of labor gymnastics wearing a uniform (UNI) and specific exercise clothes (SEC).
Adriana Seára Tirloni, Antônio Renato Pereira Moro   +1 more
doaj   +1 more source

Investigation the efficacy of intra-articular prolotherapy with erythropoietin and dextrose and intra-articular pulsed radiofrequency on pain level reduction and range of motion improvement in primary osteoarthritis of knee.

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2014
Osteoarthritis is one of the most common diseases and the knee is the most commonly affected joint. Intra-articular prolotherapy is being utilized in acute and chronic pain management setting. This study was designed to compare the efficacy of three methods of intra-articular knee joint therapies with erythropoietin, dextrose, and pulsed radiofrequency.
Poupak Rahimzadeh, Farnad Imani, Seyed Faiz, Saeed Reza Entezary, Ali Akbar Nasiri, Mohsen Ziaeefard   +5 more
openaire   +2 more sources

Nanozyme‐Reinforced miR‐197‐3p Delivery Resets Metabolic and Senescence Pathways to Rejuvenate Osteoarthritic Cartilage

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a progressive and disabling joint disease driven by oxidative stress, chondrocyte senescence and extracellular matrix (ECM) degradation, yet lacks effective disease‐modifying treatments. In this study, we identified miR‐197‐3p as a previously unrecognized, cartilage‐protective miRNA significantly downregulated in both ...
Xuejie Cai, Zehui Lv, Chen Zhang, Xingdong Yang, Ruoying Wang, Yixin Bian, Jiawei Xu, Han Wang, Yingjie Wang, Long Bai, Jiacan Su, Xisheng Weng   +11 more
wiley   +1 more source

Goniometry and fleximetry measurements to assess cervical range of motion in individuals with chronic neck pain: a validity and reliability study

BMC Musculoskeletal Disorders
Purpose To assess the test–retest and inter-rater reliability of goniometry and fleximetry in measuring cervical range of motion in individuals with chronic neck pain. Methods A reliability study.
Gabriel Gardhel Costa Araujo, André Pontes-Silva, Plínio da Cunha Leal, Bruno Sousa Gomes, Maisa Lopes Reis, Sâmira Kennia de Mello Pereira Lima, Cid André Fidelis-de-Paula-Gomes, Almir Vieira Dibai-Filho   +7 more
doaj   +1 more source

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

Advanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li, Simin Chen, Huijuan Hu, Shiyao Wu, Jingnan Wang, Kai Sun, Chenxi Peng, Suling Liu, Shuoyang Zhang, Yu Kuang, Wei Chen, Qian Qiu, Liuqin Liang, Yu Wen, Hanshi Xu, Youjun Xiao   +15 more
wiley   +1 more source

Análise da variação dos valores da rotação medial conforme a posição da diáfise do úmero Analysis on the variation of medial rotation values according to the position of the humeral diaphysis

Revista Brasileira de Ortopedia, 2012
OBJETIVO: Analisar a validade da medida de rotação medial (RM) do ombro pelos níveis vertebrais conforme a variação da posição da diáfise do úmero, testando o bigoniômetro como novo instrumental de aferição.
Alberto Naoki Miyazaki, Marcelo Fregoneze, Pedro Doneux Santos, Luciana Andrade da Silva, Guilherme do Val Sella, Carina Cohen, Taís Stedile Busin Giora, Sergio Luiz Checchia, Fabio Raia, Hélio Pekelman, Raquel Cymrot   +10 more
doaj   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

Advanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu, Shengzhao Xiao, Di Huang, Xuesong Wang, Yanwei Cao, Xiaodan Sun, Nicholas Dunne, Xiaoming Li   +7 more
wiley   +1 more source

In Situ Profiling of Nanoscale Strains Uncovers Mechano‐Architectural Predictors of Aging and Osteoarthritis Emergence

Advanced Science, EarlyView.
In situ mechanical loading of osteoarthritis‐prone murine knee joints reveals that spatial alterations in subchondral plate microarchitecture precede cartilage loss and promote a shift from coordinated epiphyseal strain dissipation in healthy joints to focal subchondral strain concentration in osteoarthritis‐prone joints.
Aikta Sharma, Lucinda A. E. Evans, Lucie E. Bourne, Jishizhan Chen, Alissa L. Parmenter, Joseph Brunet, Kamel Madi, Sebastian Marussi, Andrew A. Pitsillides, Peter D. Lee, Katherine A. Staines   +10 more
wiley   +1 more source