Results 1 to 10 of about 329,448 (411)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Handbook of California Articulation Policies and Procedures, 1986-87
Summarizing standards for admission and educational requirements at institutions of higher education in California.This collection consists of over 2600 reports generated by or about the California State University. Reports 1904-present.
Articulation Council of California
core
Publisher Correction: Effect of small heat release and viscosity on thermal-diffusive instability
Keigo Wada
doaj +1 more source
THE ARTICULATION OF THE NOTES IN TREATIES DEDICATED TO WOODWIND INSTRUMENTS FROM THE BAROQUE ERA
The articulations described in the treaties from the baroque era give proof to a wider variety, compared to the ones used in our days. The knowledge and application of these types of articulations offers a possibility to spread and enrich the expression
Ignác Csaba FILIP
doaj
The Role of Temporal Modulation in Sensorimotor Interaction
How do we align the distinct neural patterns associated with the articulation and the acoustics of the same utterance in order to guide behaviors that demand sensorimotor interaction, such as vocal learning and the use of feedback during speech ...
Louis Goldstein
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
In a language-deficient domain such as buoyancy, students generally find it difficult to explain phenomena that daily saturate their lives such as sinking and floating.
Kor, AL
core
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Learner Motivation and Teaching Aims of Japanese Language Instruction in Slovenia
The purpose of this paper is to describe Japanese language teaching and the role of language teachers in Slovenia. Firstly, this paper shows the development and current situation of Japanese language teaching in Slovenia and Central Eastern Europe based ...
Nagisa MORITOKI ŠKOF
doaj +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source

