Results 101 to 110 of about 6,877,980 (390)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Yapay Zekâ Sanatının Doğal ve Yapay Kavramına Tarihsel Süreçte Etkisi

Felsefe Dünyası
Sanat tarihsel ve teknolojik değişimlerle kendini sürekli yeniler. Antik Yunan'ın mimesis odaklı sanatı, doğayı taklit ederek gerçeklikle sanat arasında sınır çizerken, 20. yüzyılda bu sınırlar belirsizleşmiştir.
Betül Yıldırım
doaj   +1 more source

The Human Antimicrobial Peptides Dermcidin and LL-37 Show Novel Distinct Pathways in Membrane Interactions

Frontiers in Chemistry, 2017
Mammals protect themselves from inflammation triggered by microorganisms through secretion of antimicrobial peptides (AMPs). One mechanism by which AMPs kill bacterial cells is perforating their membranes.
Kornelius Zeth, Enea Sancho-Vaello
doaj   +1 more source

Quantum phases in artificial molecules

, 2001
The many-body state of carriers confined in a quantum dot is controlled by the balance between their kinetic energy and their Coulomb correlation. In coupled quantum dots, both can be tuned by varying the inter-dot tunneling and interactions.
Adourian, Amaha, Asano, Ashoori, Austing, Bayer, Beenakker, Bennet, Bimberg, Biolatti, Blick, Blick, Blick, Brodsky, Bryant, Burkard, Chakraborty, Chen, Chen, Crouch, Elisa Molinari, Eto, Fafard, Filippo Troiani, Fujisawa, Golden, Golden, Guy Austing, Hartmann, Haug, Hu, Hu, Imamura, Imamura, Imamura, Jacak, Kaputnika, Kastner, Klimeck, Kohn, Kotlyar, Kouwenhoven, Kouwenhoven, Kouwenhoven, Landau, Livermore, Lloyd, Lockwood, Lozovik, Maksym, Martı́n-Moreno, Massimo Rontani, Mattis, Matveev, Matveev, Mayrock, Nagaraja, Oh, Oosterkamp, Oosterkamp, Palacios, Partoens, Partoens, Partoens, Partoens, Pfannkuche, Pi, Rontani, Rontani, Rontani, Schedelbeck, Schmidt, Schüller, Slater, Stafford, Tamura, Tarucha, Tokura, Troiani, Ulrich Hohenester, van der Vaart, Wagner, Wang, Waugh, Waugh, Wensauer, Woggon, Yannouleas, Zrenner   +88 more
core   +1 more source

Checklist for Artificial Intelligence in Medical Imaging (CLAIM): 2024 Update.

Radiology: Artificial Intelligence
"Just Accepted" papers have undergone full peer review and have been accepted for publication in Radiology: Artificial Intelligence. This article will undergo copyediting, layout, and proof review before it is published in its final version.
Ali S. Tejani, M. Klontzas, Anthony A Gatti, John T Mongan, Linda Moy, Seong Ho Park, Charles E. Kahn   +6 more
semanticscholar   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Relationship between maternal arterial and foetal cord carbon dioxide tension and neonatal outcome in critically ill pregnant women at delivery

Indian Journal of Anaesthesia
Background and Aims: No studies have evaluated the relationship between maternal arterial partial pressure of carbon dioxide (mPaCO2) and umbilical cord venous partial pressure of carbon dioxide (PCO2) in critically ill pregnant women at delivery.
Katelyn T Scharf, Shobana Bharadwaj, Allison Lankford, Michael Wong, Bhavani S Kodali   +4 more
doaj   +1 more source

Analyzing Barriers and Enablers for the Acceptance of Artificial Intelligence Innovations into Radiology Practice: A Scoping Review [PDF]

, 2023
Fatma A. Eltawil, Michael Atalla, Emily Boulos, Afsaneh Amirabadi, Pascal N. Tyrrell   +4 more
openalex   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source