Results 81 to 90 of about 3,013,083 (257)

Imaging of aortic valve dynamics in 4D OCT

Current Directions in Biomedical Engineering, 2015
The mechanical components of the heart, especially the valves and leaflets, are enormous stressed during lifetime. Therefore, those structures undergo different pathophysiological tissue transformations which affect cardiac output and in consequence ...
Schnabel Christian, Jannasch Anett, Faak Saskia, Waldow Thomas, Koch Edmund   +4 more
doaj   +1 more source

Mechanically Regulated Secretion: How Physical Forces Instruct the Secretory Pathway and Remodel the Secretome

Advanced Science, EarlyView.
Mechanical cues, including ECM stiffness, stretch, compression, shear stress, and traction forces, remodel trafficking across the secretory pathway, from the ER and Golgi to endolysosomal compartments and the plasma membrane. The resulting secretome reshapes ECM composition and tissue mechanics, establishing feedback loops that support homeostasis or ...
Domenico Russo, Seetharaman Parashuraman, Maria Luigia Maresca, Angela Francesca Dinoi, Alessia Calcagnì, Riccardo Rizzo   +5 more
wiley   +1 more source

Cardiac safety of repetitive transcranial magnetic stimulation in bulimic eating disorders

, 2011
BackgroundRepetitive transcranial magnetic stimulation (rTMS) is increasingly used in research. However, cardiac safety is not routinely assessed.ObjectiveThis study aims to investigate cardiac safety of rTMS in people with a bulimic eating disorder ...
Ulrike Schmidt, Angélica M. Claudino, Campbell, Iain, Van den Eynde, Frederique, Frederique Van den Eynde, Daniel Stahl, Stahl, Daniel; id_orcid, Stahl, Daniel, Horrell, Linda, Schmidt, Ulrike, Claudino, Angelica M., Claudino, Angelica M. [UNIFESP], Iain Campbell, Linda Horrell, Andiappan, Manoharan, Manoharan Andiappan   +15 more
core   +1 more source

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

Advanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin, Jiani Li, Panqin Ma, Shinan Wu, Wenying Guan, Yimin Huang, Ke Feng, Mingyan Wei, Zixuan Yang, Shujia Guo, Caihong Huang, Yun‐Long Wu, Yi Han, Zuguo Liu   +13 more
wiley   +1 more source

Engineering the Cellular Microenvironment for Human Induced Pluripotent Stem Cell Cardiac Differentiation: Beyond Wnt Signaling

Bioengineering
Human induced pluripotent stem cells (hiPSCs) have revolutionized cardiovascular research by providing a renewable source of patient-specific cardiomyocytes for disease modeling, drug discovery, precision medicine, and regenerative therapies.
Gustavo Rosero, Ana Belén Peñaherrera-Pazmiño, Camilo Pérez-Sosa   +2 more
doaj   +1 more source

Cardiac biopotentials influence on central nervous system functioning: first steps in hypothesis verification [PDF]

Саратовский научно-медицинский журнал, 2012
The research goal is to verify the hypothesis on influence of cardiac biopotentials on central nervous system. Materials: 20 healthy individuals aged 18-26 years old have been participated in the investigations.
Kondal'skaya Yu.O., Cherkasova S.A., Shvarts Yu.G.   +2 more
doaj  

Liquid Metal Enabled Electrobiology: A New Frontier to Tackle Disease Challenges

Micromachines, 2018
In this article, a new conceptual biomedical engineering strategy to tackle modern disease challenges, called liquid metal (LM) enabled electrobiology, is proposed.
Xuelin Wang, Yi Ren, Jing Liu
doaj   +1 more source

Ultrasound‐Triggered piRNA Delivery Using Biomimetic Phase‐Changeable Nanoparticles for Theranostics of Myocardial Infarction

Advanced Science, EarlyView.
A biomimetic ultrasound‐responsive piRNA delivery nanoparticle platform (piR‐NPs) enables targeted delivery and ultrasound (US)‐triggered release of piR‐1873 in infarcted myocardium. The released piR‐1873 suppresses Usp2‐mediated RIP1/RIP3/MLKL necroptosis, reduces myocardial injury and fibrosis, and promotes cardiac functional recovery, providing a ...
Yajun Zhang, Hongzhao Qi, Yanyan Yang, Feng Wang, Tiantian Han, Yanbei Lei, Xiaolu Li, Zhibin Wang, Hua Qu, Tao Yu, Pin Sun   +10 more
wiley   +1 more source

Stabilizing Functional Nucleic Acids for Real‐Sample Diagnostics

Angewandte Chemie, EarlyView.
Functional nucleic acids enable programmable real‐sample diagnostics, but often lose function in complex biological matrices. This review highlights four stabilization levers—chemical, topological, architectural, and microenvironment/interface engineering—that preserve aptamer and DNAzyme performance in saliva, serum, urine, and stool, reframing ...
Soyeon Lee, Letizia Dondi, Amal Mathai, Connor Nurmi, Yingfu Li   +4 more
wiley   +2 more sources

Perfil clínico de pacientes chagásicos e não-chagásicos portadores de marca-passo cardíaco artificial Clinical profile of Chagas and non-Chagas' disease patients with cardiac pacemaker

Revista da Sociedade Brasileira de Medicina Tropical, 2006
O objetivo do estudo foi comparar pacientes chagásicos e não-chagásicos com marca-passo cardíaco artificial uni ou bicameral quanto à fração de ejeção do ventrículo esquerdo, o limiar de estimulação ventricular e a incidência de arritmias cardíacas ...
Leonor Garcia Rincon, Manoel Otávio da Costa Rocha, Marco Túlio Baccarini Pires, Bruna Guimarães Oliveira, Vladimir da Costa Val Barros, Marcio Vinicius Lins Barros, Antônio Luiz Pinho Ribeiro   +6 more
doaj   +1 more source