Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
BuildingsLighting systems in sports venues have a significant impact on both the user experience and quality of events. However, owing to the large number of luminaires, high individual lamp power, and strict lighting standards, the lighting energy consumption of
Sirui Rao, Chen Wang, Zeyu Li, Ying Yu
doaj +1 more source
Analisis Sistem Pencahayaan di Ruang Sipil/sarana dengan Sni Nomor 03-6575-2001 Tentang Perancangan Sistem Pencahayaan Buatan PT X Gresik [PDF]
, 2015 Intensityilluminationforoffice activityless than according to SNI 03-6575-2001 number 350 lux.Indoor lighting, especially in the workplace that does not meet certain requirements can worsen vision.Less of lighting will cause eyestrain which will then be ...
Denny, H. M. (Hanifa) +2 more
core
Progressing the rights to light debate: Part 2: the grumble point revisited [PDF]
, 2005 Purpose - The paper examines the origins of the so-called "grumble point" (a sky factor of 0.2 per cent) as the measure of daylight adequacy in rights to light disputes.
Chynoweth, P
core +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
An investigation of the role of artificial lighting in the process of creating a pleasant affective spacial meaning: A case study of Dahd Hotel in Yazd [PDF]
کاوشهای جغرافیایی مناطق بیابانی, 2020 Due to its being located in a desert area, the city of Yazd has a favorable weather and a clear starry sky at nighttime. So, has the potential to expand nightlife and become a "24-hour city".
Neda Khaksar +2 more
doaj
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Kontribusi Pencahayaan Buatan terhadap Kualitas Visual Bangunan pada Malam Hari
Ruang-Space: Jurnal Lingkungan Binaan, 2018 Historical buildings frequently appear distinctive in their architectural style and ornament. These buildings have an emotional impact and forms of association to eye-witnesses.
Ariani Mandala, Vania Sheila
doaj +1 more source
Recommended cucumber hybrids for growing in greenhouses under conditions artificial lighting
Овощи России, 2021 For plants, light is a determining factor in growth and development. The use of artificial lighting in greenhouses has a huge impact on the yield, cost and timing of the receipt of vegetable products.
V. G. Korol
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source