Results 51 to 60 of about 39,154 (217)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Shedding light on the dark: Does artificial illumination affect mammal activity at waterholes in sub‐Saharan Africa?

Conservation Science and Practice
Artificial lighting is increasingly used at waterholes in tourism areas to enhance nocturnal wildlife viewing, yet its effects on animal behavior remain poorly understood.
Jessica R. Patterson, Stéphanie Périquet‐Pearce, James C. Beasley   +2 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

The impact of artificial lighting on improving the visual experience of museum visitors: A case study of Sharjah Museum of Islamic Civilization

Heritage and Sustainable Development
Lighting is a crucial element in museum design, directly influencing visitors’ psychological responses, visual experience, and overall satisfaction. Despite its significance, limited research exists on artificial lighting in museums within the United ...
Meera Alketbi, Emad Mushtah
doaj   +1 more source

Artificial lighting within Saratov and the Saratov region: Territorial differences and dynamics in 2007–2022 [PDF]

Известия Саратовского университета. Новая серия: Серия Науки о Земле
The increase in illumination levels in populated areas, including as a result of the implementation of several federal projects, has raised concerns about light pollution caused by artificial lighting.
Preobrazhenskiy, Yuriy Vladimirovich, Borshchyov, Eugen I.   +1 more
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Investigation of Lighting Performance and Improvement of Efficiency in a Designated Area of an Active Educational Building

Gazi Üniversitesi Fen Bilimleri Dergisi
Due to the inefficient use of daylight in many areas, the demand for artificial light sources, which have a history of approximately 200 years, has increased.
Erşan Ömer Yüzer
doaj   +1 more source

A Survey on the Intensity of Lighting in Elementary Schools of Bojnurd City

بهداشت کار و ارتقای سلامت, 2022
Background and Aim: Optimal lighting should create a balance between economy and the environment. In order to comply with safety and health principles of the staff, proper lighting of the work environment should be provided for everyday tasks ...
Faeze SEPAHI ZOERAM, Fateme PAKRAVAN, Morteza ESMAILZADE KAVAKI, Neda VAHIDI   +3 more
doaj