Results 41 to 50 of about 848,733 (323)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

On the relationship between predictive coding and backpropagation.

open access: yesPLoS ONE, 2022
Artificial neural networks are often interpreted as abstract models of biological neuronal networks, but they are typically trained using the biologically unrealistic backpropagation algorithm and its variants.
Robert Rosenbaum
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Convolutional Neural Networks Applied to the Performance of a Coffee Tree [PDF]

open access: yesE3S Web of Conferences
The use of artificial neural networks has been a significant advancement in the field of computer science, as it supports various fields of study in many traditional sciences. Over the years, numerous models of artificial neural networks have been tested,
Oscar Sánchez Tinoco   +2 more
doaj   +1 more source

Optimal Artificial Neural Network Type Selection Method for Usage in Smart House Systems

open access: yesSensors, 2020
In the process of the “smart” house systems work, there is a need to process fuzzy input data. The models based on the artificial neural networks are used to process fuzzy input data from the sensors. However, each artificial neural network has a certain
Vasyl Teslyuk   +3 more
doaj   +1 more source

Theoretical Interpretations and Applications of Radial Basis Function Networks [PDF]

open access: yes, 2003
Medical applications usually used Radial Basis Function Networks just as Artificial Neural Networks. However, RBFNs are Knowledge-Based Networks that can be interpreted in several way: Artificial Neural Networks, Regularization Networks, Support Vector ...
Blanzieri, Enrico
core  

A Neural Algorithm of Artistic Style

open access: yes, 2015
In fine art, especially painting, humans have mastered the skill to create unique visual experiences through composing a complex interplay between the content and style of an image.
Bethge, Matthias   +2 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Concept transfer of synaptic diversity from biological to artificial neural networks

open access: yesNature Communications
Recent developments in artificial neural networks have drawn inspiration from biological neural networks, leveraging the concept of the artificial neuron to model the learning abilities of biological nerve cells.
Martin Hofmann   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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