Results 111 to 120 of about 1,603,738 (220)

Does human evolution in different latitudes influence susceptibility to obesity via the circadian pacemaker?

open access: yes, 2012
The variable photoperiods of Northern latitudes challenge the entrainment capacity of the circadian pacemaker, which evolved under constant photoperiods in Equatorial regions.
Wyse, C.A.
core   +1 more source

Multitarget Drug Design for Cardiovascular Disease: Bridging Chemistry and Medicine

open access: yesChemMedChem, Volume 21, Issue 19, 14 October 2026.
Many pathophysiological pathways associated with cardiovascular diseases involve multiple drug targets. This article reviews recent advances in the development of pharmacological compounds capable of simultaneously modulating multiple mechanisms. Multitarget drugs offer a promising therapeutic approach for complex cardiovascular disorders, including ...
Gyuzel Y. Mitronova   +3 more
wiley   +1 more source

Cortisol Dynamics at High Temporal Resolution For Wearable Biosensor Research

open access: yesAdvanced Sensor Research, Volume 5, Issue 10, October 2026.
High‐frequency cortisol profiling reveals that endocrine responses depend strongly on both stressor type and the individual. Circadian sampling shows a consistent morning‐to‐evening decline, while cold exposure elicits delayed rises and exercise and cognitive challenges produce divergent trajectories.
Munia Ferdoushi   +3 more
wiley   +1 more source

Survey of ST-Segment Changes due to Active Lead Fixation during Permanent Pacemaker Device Implantation as a Prognostic Indicator of its Performance

open access: yesمجله دانشکده پزشکی اصفهان, 2017
Background: Active lead implantation can create injury in myocardium that may be associated with a ST-segment elevation. This ST-segment elevation may be correlated with changes in other parameters such as threshold, sense, amplitude, impedance, and ...
Sima Sayah   +2 more
doaj  

A Dual‐Modal Wearable PPG Smartwatch with AI‐Enhanced Correction for High‐Accuracy and Continuous AF Burden Assessment

open access: yesAdvanced Science, Volume 13, Issue 56, 9 October 2026.
ABSTRACT Atrial fibrillation (AF) increases the risk of stroke and heart failure, yet accurate quantification of AF burden in daily life remains difficult. Although smartwatch photoplethysmography (PPG) supports continuous monitoring, complex rhythms and signal noise can impair burden estimation.
Song Zuo   +27 more
wiley   +1 more source

Post-Implant Global Longitudinal Strain as a Predictor of Pacing-Induced Cardiomyopathy in Patients with Preserved Ejection Fraction Undergoing Pacemaker Placement

open access: yesReviews in Cardiovascular Medicine
Background: Right ventricular (RV) pacing exacerbates heart failure and increases cardiac mortality in patients with reduced ejection fraction (EF).
Sung Soo Kim   +2 more
doaj   +1 more source

Explorations into development of a neurally regulated cardiac pacemaker

open access: yes, 1995
Although the artificial cardiac pacemaker has contributed to the management of patients with serious arrhythmias, its rate-responsive function is not sufficient to provide physiological regulation of heart rate (HR).
O. Kawaguchi   +7 more
core   +1 more source

Repetitive Transcranial Magnetic Stimulation Combined With Median Nerve Electrical Stimulation for Severe Traumatic Brain Injury

open access: yesBrain and Behavior, Volume 16, Issue 10, October 2026.
Combining top‐down rTMS over the left DLPFC with bottom‐up right median nerve stimulation markedly outperformed either modality alone, awakening 93% of patients with severe TBI by week 4 and improving EEG, hemodynamics, and GCS—supporting dual‐pathway neuromodulation as a safe, high‐efficacy strategy for coma recovery.
Nana Wang, Manrong Li, Guozhen Zhang
wiley   +1 more source

Study of the control system of a pacemaker for the heart rate regulation

open access: yes
reservedI pacemaker sono dei dispositivi elettro-medicali che emettono degli impulsi elettrici con lo scopo di ristabilire il normale ritmo cardiaco per garantire ai tessuti la corretta erogazione di ossigeno.
CUDICIO, GIADA
core  

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