Results 191 to 200 of about 73,779 (261)

ApoJ regulates endothelial lipase activity and stability

open access: yesProtein Science, Volume 35, Issue 4, April 2026.
Abstract Endothelial lipase (EL) is a key regulator of high‐density lipoprotein (HDL) metabolism. Many aspects of EL function remain incompletely understood due to challenges in purifying active EL. This study identifies apolipoprotein J (ApoJ) as a novel chaperone for EL, crucial for its solubility and activity.
Uriel L. Jean‐Baptiste   +5 more
wiley   +1 more source

Developing and Evaluating Aquatic Passive Sampling of Environmental DNA for Microbial Community Profiling

open access: yesMolecular Ecology Resources, Volume 26, Issue 3, April 2026.
ABSTRACT Environmental DNA (eDNA) metabarcoding has transformed biodiversity monitoring across taxa from bacteria to mammals, yet sample collection remains a major bottleneck. Passive sampling via adsorption and entrapment has emerged as a promising alternative to overcome the limitations of conventional active filtration.
Cheng Qian   +6 more
wiley   +1 more source

Gut Luminal Exosomes in Young and Old Mice: Multi‐Omic Characteristics and Regulation of Gut Permeability

open access: yesAging Cell, Volume 25, Issue 4, April 2026.
This graphical abstract shows that gut luminal exosomes (LFEs) change with aging, with old mice producing LFEs that disrupt gut barrier integrity, alter microbiome composition, and promote insulin resistance. In contrast, LFEs from young mice improve gut barrier function and metabolic health, and transferring these LFEs can partially reverse age ...
Abdelnaby Khalyfa   +3 more
wiley   +1 more source

Prioritising research on endocrine disruption in the marine environment: a global perspective

open access: yesBiological Reviews, Volume 101, Issue 2, Page 848-868, April 2026.
ABSTRACT A healthy ocean is a crucial life support system that regulates the global climate, is a source of oxygen and supports major economic activities. A vast and understudied biodiversity from micro‐ to macro‐organisms is integral to ocean health.
Patricia I. S. Pinto   +23 more
wiley   +1 more source

Comparative analysis of morphology, growth performance and gonadal development between the hybrid crab (Scylla serrata ♀ × S. paramamosian ♂) and S. serrata

open access: yesJournal of the World Aquaculture Society, Volume 57, Issue 2, April 2026.
Abstract Interspecific hybridization, through integrating genetic resources across distinct species, serves as a pivotal strategy for improving yield, stress resistance, and quality in aquacultural species. To evaluate the performance of hybrid crab (Scylla serrata ♀ × S.
Huanyu Zhang   +7 more
wiley   +1 more source

Quasi‐Periodic Behavior of Tropical Cyclone Precursors and Its Phase Matching With the Insolation Diurnal Cycle

open access: yesGeophysical Research Letters, Volume 53, Issue 5, 16 March 2026.
Abstract The formation of tropical cyclones (TCs) remains a significant scientific challenge. Here, we demonstrate that robust quasi‐periodic behavior (QPB) emerges during TC genesis with idealized numerical simulations. The QPB is an internal mode of the TC precursor, whose underlying mechanism is a convectively coupled inertia‐gravity oscillation ...
Bolei Yang   +4 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, Volume 20, Issue 3, Page 804-822, March 2026.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Exploiting Two‐Photon Lithography, Deposition, and Processing to Realize Complex 3D Magnetic Nanostructures

open access: yesAdvanced Functional Materials, Volume 36, Issue 20, 9 March 2026.
Two‐photon lithography (TPL) enables 3D magnetic nanostructures with unmatched freedom in geometry and material choice. Advances in voxel control, deposition, and functionalization open pathways to artificial spin ices, racetracks, microrobots, and a number of additional technological applications.
Joseph Askey   +5 more
wiley   +1 more source

Upconversion Nanoparticles Embedded Photonic Contact Lens for Transepithelial Corneal Crosslinking Using Hyaluronate – Riboflavin Conjugate

open access: yesAdvanced Functional Materials, Volume 36, Issue 22, 16 March 2026.
A minimally invasive, transepithelial corneal cross‐linking (TE‐CXL) approach is presented using upconversion nanoparticles (UCNPs)‐loaded contact lenses (UCLs), after topical delivery of hyaluronate–riboflavin conjugates. The NIR‐to‐UV/blue light conversion by UCNPs in a UCL can activate riboflavin for TE‐CXL, resulting in the biomechanical strength ...
Gibum Lee   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy