Results 101 to 110 of about 535,122 (305)
The Clinical Spectrum and Neurodevelopmental Pathogenesis of KPTN‐Related Disorder in a Mouse Model
Annals of Neurology, EarlyView.Objective Pathogenic variants in Kaptin (KPTN) cause KPTN‐related disorder (KRD). KPTN modulates mTOR signaling activation within the KICSTOR complex in response to cellular amino acid levels. We define the clinical spectrum and investigate the developmental pathogenesis of KRD.
Lettie E. Rawlins +104 more
wiley +1 more source
A Scoping Review of Programs of Active Arts Engagement in International Medical Curricula
Perspectives on Medical EducationIntroduction: Arts and humanities are often positioned as ‘additive’ to medical education, rather than ‘intrinsic’. They are also used to teach skills and perspective-taking more than utilising their transformative potential to propel personal insight ...
Zoe Moula +7 more
doaj +1 more source
Increased Numbers of CD4+ T‐Cells in the Hypocretin/Orexin Region of Narcolepsy Type 1
Annals of Neurology, EarlyView.Narcolepsy type 1 (NT1) is presumed to be an autoimmune disorder caused by hypothalamic loss of hypocretin (Hcrt; orexin). In postmortem NT1 brains, we observed an 11‐fold increase of CD4+ T‐cells in the Hcrt region compared with control hypothalami, without a corresponding rise in CD8+ T‐cells.
Ling Shan +5 more
wiley +1 more source
Open Access – What’s New in the Arts & Humanities?
, 2015 Learn about some of the newest open access publications and platforms designed to support the open sharing of humanities research. Join a discussion with librarian liaisons to arts and humanities departments about how Gettysburg faculty and the library ...
Scholarly Communications,
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Angewandte Chemie, EarlyView.Das Dimer der Pyrrolysyl‐tRNA‐Synthetase zeigt im katalytischen Zyklus einen alternierenden Wirkmodus seiner Monomere, der durch die Belegung sekundärer Bindungsstellen an den Intermonomer‐Grenzflächen außerhalb der katalytischen Bindungsstelle realisiert wird.
Jessica Dröden +6 more
wiley +1 more source
Angewandte Chemie, EarlyView.Bei der Suche nach neuen allosterischen Stellen in der Serin/Threonin‐Kinase p38α deckt die NMR‐Spektroskopie eine dynamische Kopplung zwischen dem katalytischen Zentrum und der Lipidtasche auf. Die Ergebnisse offenbaren bewegungsbezogene Interdependenzen, die entfernte Regionen des Enzyms miteinander verbinden, was die Lipidtasche als ...
Sara Medina Gómez +4 more
wiley +1 more source
Incite 2011: The power of art, March 10-14, 2011 [PDF]
, 2011 This is the concert program of the Incite 2011: The power of art performance on Thursday - Monday, March 10 - 14, 2011 at 8:00 p.m., at the BMCC Tribeca Performing Arts Center, 199 Chambers Street, New York, New York.
School of Music, Boston University
core
The myth of the Humanities in crisis
Digithum, 2004 Denying from the start that Humanities are in crisis, the author examines certain aspects of this statement, reflecting on what is meant by stating that the Humanities are in crisis, arguing for the growing interest in human sciences and looking more ...
Josep Maria Terricabras
doaj
Arts, Humanities, Medicine, and Discovery: a Creative Calling. [PDF]
J Gen Intern Med, 2020 Charon R, Ship A, Asch SM.
europepmc +1 more source
Angewandte Chemie, EarlyView.Der bimetallische M14‐Cluster [Co3Ga2]H(μ2‐GaTMP)9 wurde durch einen ko‐reduktiven Ansatz erzielt. Dieser Ansatz nutzt Mg und H2, um den Ga‐TMP‐Liganden selektiv zu entschützen und das TMP abzufangen, was zur Bildung eines gemischtmetallischen Co/Ga Clusterkerns führt, was diesen zu einem strukturellen Vertreter eines vergleichbaren Gegenstücks der ...
Fabrizio E. Napoli +6 more
wiley +1 more source