Results 191 to 200 of about 154,972 (315)

Retraction notice to "The role of chromium supplementation in cardiovascular risk factors: A comprehensive reviews of putative molecular mechanisms" [Heliyon 9 (2023) e19826]. [PDF]

open access: yesHeliyon
Gossa Al-Saadde DL   +9 more
europepmc   +1 more source

Intermolekulare, Enantioselektive Nickel‐Katalysierte Arylierung von Nicht‐Aktivierten C(sp3)–H Bindungen

open access: yesAngewandte Chemie, EarlyView.
Ni: neue Lösung für asymmetrische C(sp3)‐H‐Aktivierung. Die stereoselektive Synthese vollständig kohlenstoffsubstituierter quartärer Stereozentren gelingt durch eine enantioselektive C(sp3)‐H‐Arylierung unter Verwendung eines Ni‐Katalysators auf der Basis eines BINOL‐Derivaten.
Erwan Brunard   +4 more
wiley   +1 more source

Targeting the Spliceosomal Protein USP39 Through Allosteric Ligands and PROTAC‐Induced Degradation

open access: yesAngewandte Chemie International Edition, EarlyView.
Proteolysis‐targeting chimeras (PROTACs) enable degradation of proteins previously considered undruggable by harnessing the cellular ubiquitin–proteasome system. In this study, Schäfer et al. identify thiazole‐based small molecules that allosterically bind the zinc finger domain of ubiquitin‐specific protease 39 (USP39), a non‐enzymatic scaffold ...
Daniel Schäfer   +11 more
wiley   +1 more source

General characteristics of injuries in martial arts

open access: yesМartial arts
Purpose: using the analysis of scientific, methodological, medical and specialized literature to identify the main causes and means of injury prevention in martial arts. Material and methods. During the work, the following research methods were used to solve the assigned tasks: analysis, systematization and generalization of scientific and scientific ...
openaire   +1 more source

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