Enantiomer stability of atropisomeric 1,5-disubstituted 1,2,3-triazoles
Tetrahedron Chem, 2022 The synthesis and characterisation of axially chiral atropisomeric 1,5-disubstituted 1,2,3-triazoles is reported. Molecules designed to display restricted rotation about 1,2,3-triazole N-1-aryl or 1,2,3-triazole C-5-aryl bonds were investigated by ...
Fernanda Meloni +6 more
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Boron Arylations of Subporphyrins with Aryl Zinc Reagents [PDF]
Chemistry – A European Journal, 2016 AbstractBoron arylations of B‐(methoxo)triphenylsubporphyrin have been developed with a combined use of ArZnI⋅LiCl and trimethylsilyl chloride. Aryl zinc reagents bearing bromo, cyano, amide, and ester groups can be employed for the B‐arylation reaction to provide the corresponding B‐arylated subporphyrins in moderate yields.
Kotani, Ryota +3 more
openaire +3 more sources
Direct Introduction of a Dimesitylboryl Group Using Base-Mediated Substitution of Aryl Halides with Silyldimesitylborane [PDF]
, 2016 The first dimesitylboryl substitution of aryl halides with a silylborane bearing a dimesitylboryl group in the presence of alkali-metal alkoxides is described.
Albrecht +68 more
core +1 more source
Iron-Catalyzed, Highly Regioselective Synthesis of alpha-Aryl Carboxylic Acids from Styrene Derivatives and CO2 [PDF]
, 2012 The iron-catalyzed hydrocarboxylation of aryl alkenes has been developed using a highly active bench-stable iron(II) precatalyst to give alpha-aryl carboxylic acids in excellent yields and with near-perfect regioselectivity. Using just 1 mol % FeCl2, bis(
Greenhalgh, Mark D., Thomas, Stephen P.
core +1 more source
Manganese carbonyl-mediated reactions of azabutadienes with phenylacetylene, methyl acrylate and other unsaturated molecules [PDF]
, 2004 Reaction of PhCH₂Mn(CO)₅ with l,4-di-aryl-1-aza-1,3-butadienes gave substituted pyrrolinonyl rings which were η⁴-coordinated to a Mn(CO)₃ group. These are formed by intramolecular CO insertion into a (non-isolated) cyclomanganated intermediate, followed ...
Mace, Wade +3 more
core +2 more sources
Molecules, 2021 We describe a mechanism-guided discovery of a synthetic methodology that enables the preparation of aromatic amides from 2-bromo-2,2-difluoroacetamides utilizing a copper-catalyzed direct arylation.
Satenik Mkrtchyan +4 more
doaj +1 more source
Semiheterogeneous Dual Nickel/Photocatalytic (Thio)etherification Using Carbon Nitrides [PDF]
, 2019 A carbon nitride material can be combined with homogeneous nickel catalysts for light-mediated cross-couplings of aryl bromides with alcohols under mild conditions.
Cavedon, Cristian +3 more
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High throughput synthesis of 2,5-substituted indoles using a titanium carbenoid bearing boronate functionality [PDF]
, 2008 A titanium benzylidene complex bearing a boronate group converted resin-bound esters into enol ethers. Suzuki cross-coupling with aryl iodides followed by cleavage with acid completed the solid-phase synthesis of 2,5-disubstituted N-Boc-indoles.
Hartley, R.C. +3 more
core +1 more source
Synthesis of Morphinans through Anodic Aryl‐Aryl Coupling
The Chemical Record, 2021 AbstractThe morphinans are an important class of structurally fascinating and physiologically important natural products as exemplified by the famous opium alkaloids of the morphine family. Although this class of secondary metabolites from the juice of the opium poppy capsule was already used for medicinal purposes thousands of years ago, chemical ...
Nina Vierengel +3 more
openaire +4 more sources
Synthesis of 2-aryl-benzothiazoles via Ni-catalyzed coupling of benzothiazoles and aryl sulfamates
Heterocyclic Communications, 2020 2-Aryl-benzothiazoles have been successfully synthesized via a simple coupling reaction between benzothiazoles and aryl sulfamates using a nickel catalyst. The nickel catalyst is inexpensive, reusable and commercially available.
Yu Xiaofeng +4 more
doaj +1 more source