Results 61 to 70 of about 405,866 (284)

Horizontal Extraocular Muscle Insertion Site in Relation to Axial Length Using Swept-Source Anterior Segment OCT

Clinical Ophthalmology, 2020
Dina El-Fayoumi,1 Nermeen Bahgat,1 Mohamed Khafagy,1 Ragai Hatata,2 Dalia Sabry,3 Ghada Allam,3 Manal Ali Kasem,3 Sherin Sadek2 1Ophthalmology Department, Faculty of Medicine, Cairo University, Cairo, Egypt; 2Ophthalmology Department, Faculty of Medicine,
El-Fayoumi D, Bahgat N, Khafagy M, Hatata R, Sabry D, Allam G, Kasem MA, Sadek S   +7 more
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Anterior Segment Optical Coherence Tomography (AS-OCT) Guided Reversal of Edematous Punctal Occlusion

Clinical Ophthalmology, 2020
Mohammed Sameh Elshorbagy, Osama E Shalaby, Mohamed Ashraf Eldesouky, Amr M Awara Oculoplasty Unit, Ophthalmology Department, Tanta University, Tanta, EgyptCorrespondence: Amr M AwaraOculoplasty Unit, Ophthalmology Department, Tanta University, Tanta ...
Elshorbagy MS, Shalaby OE, Eldesouky MA, Awara AM   +3 more
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Corneal Epithelial Thickness Profile in Healthy Portuguese Children by High-Definition Optical Coherence Tomography

Clinical Ophthalmology, 2021
Tomás de Oliveira Loureiro, Sandra Rodrigues-Barros, Diogo Lopes, Ana Rita Carreira, Filipe Gouveia-Moraes, Ana Vide-Escada, Nuno Patricio Campos Ophthalmology Department, Hospital Garcia de Orta, Almada, PortugalCorrespondence: Tomás de ...
Loureiro TO, Rodrigues-Barros S, Lopes D, Carreira AR, Gouveia-Moraes F, Vide-Escada A, Campos NP   +6 more
doaj  

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

In vivo identification of angle dysgenesis and its relation to genetic markers associated with glaucoma using artificial intelligence

Indian Journal of Ophthalmology
Purpose: To predict the presence of angle dysgenesis on anterior-segment optical coherence tomography (ADoA) by using deep learning (DL) and to correlate ADoA with mutations in known glaucoma genes.
Viney Gupta, Shweta Birla, Toshit Varshney, Bindu I Somarajan, Shikha Gupta, Mrinalini Gupta, Arnav Panigrahi, Abhishek Singh, Dinesh Gupta   +8 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Wound morphologies of sclerotomies closed with scleral massage and scleral needling techniques: A comparative study

Indian Journal of Ophthalmology
Background: This prospective study aimed to compare scleral needling with the conventional scleral massage technique for sclerotomy closure, using anterior segment optical coherence tomography (AS-OCT) to assess postoperative wound morphology.
Ebubekir Durmuş, Alev Kose, Veysel Aykut, Nursal Melda Yenerel, Halit Oğuz, Fehim Esen   +5 more
doaj   +1 more source

Assessment of sclerocorneal incision architecture after phacoemulsification using AS-OCT

Scripta Scientifica Medica, 2018
Introduction The construction of the main incision is crucial for the outcome of cataract surgery.  There are many considerations including: wound preparation and stability, surgically induced astigmatism, stability of anterior chamber, and wound closure stability with rising intraocular pressure (IOP).
Jana Simova, Mladena Radeva, Dimitar Grupchev, Christina Grupcheva   +3 more
openaire   +2 more sources