Results 161 to 166 of about 22,367 (166)

Long Noncoding RNA URB1-Antisense RNA 1 (AS1) Suppresses Sorafenib-Induced Ferroptosis in Hepatocellular Carcinoma by Driving Ferritin Phase Separation.

ACS Nano, 2023
Sorafenib, a first-line molecular-target drug for advanced hepatocellular carcinoma (HCC), has been shown to be a potent ferroptosis inducer in HCC. However, we found that there was a lower level of ferroptosis in sorafenib-resistant HCC samples than in ...
Yuan Gao, M. Tong, T. Wong, K. Ng, Yu-Nong Xie, Zhaowei Wang, Huajian Yu, J. Loh, Meng Li, Stephianie Ma   +9 more
semanticscholar   +1 more source

LncRNA PSMB8-AS1 Instigates Vascular Inflammation to Aggravate Atherosclerosis

Circulation Research, 2023
BACKGROUND: Increasing evidence suggests that long noncoding RNAs play significant roles in vascular biology and disease development. One such long noncoding RNA, PSMB8-AS1, has been implicated in the development of tumors. Nevertheless, the precise role
Shu Li, Run-Chao He, Shao-Guo Wu, Yunpeng Song, Ke-Lan Zhang, Mao-Lin Tang, Yan-Rou Bei, Ting Zhang, Jing-Bo Lu, Xin Ma, Min Jiang, Liang-Jun Qin, Yudan Xu, Xian-Hui Dong, Jia Wu, Xiao-Ping Dai, Yan-Wei Hu   +16 more
semanticscholar   +1 more source

Lnc-TMEM132D-AS1 as a potential therapeutic target for acquired resistance to osimertinib in non-small-cell lung cancer.

Molecular Omics, 2023
Acquired resistance is a major obstacle to the therapeutic efficacy of osimertinib in non-small-cell lung cancer (NSCLC). Current knowledge about the role of long non-coding RNAs (lncRNAs) in this phenomenon is insufficient.
Nan Wang, Qilin Zhao, Yutang Huang, Chunjie Wen, Ya-Jun Li, Meihua Bao, Lanxiang Wu   +6 more
semanticscholar   +1 more source

LncRNA FOXD2-AS1 promotes the growth, invasion and migration of OSCC cells by regulating the MiR-185-5p/PLOD1/Akt/mTOR pathway.

Cancer Genetics
Although lncRNAs are recognized to contribute to the development of oral squamous-cell carcinoma (OSCC), their exact function in invasion and cell migration is not clear. In this research, we explored the molecular and cellular mechanisms of FOXD2-AS1 in
Jian Liu, Yong Zhang, Jing Wu, Xin Liu, Lifang Li, Jinhong Zhang   +5 more
semanticscholar   +1 more source

Mesenchymal Stem Cell–Originated Exosomal Lnc A2M-AS1 Alleviates Hypoxia/Reperfusion-Induced Apoptosis and Oxidative Stress in Cardiomyocytes

Cardiovascular Drugs and Therapy, 2022
Hang Yu, Yuxiang Pan, Mingming Dai, Xiaoqi Wang, Haibo Chen   +4 more
semanticscholar   +1 more source