Results 21 to 30 of about 22,367 (166)

METTL3‐stabilized super enhancers‐lncRNA SUCLG2‐AS1 mediates the formation of a long‐range chromatin loop between enhancers and promoters of SOX2 in metastasis and radiosensitivity of nasopharyngeal carcinoma

Clinical and Translational Medicine, 2023
Background Super enhancers (SE) play pivotal roles in cell identity and diseases occur including tumorigenesis. The depletion of SE‐associated lncRNA transcripts, also known as super‐lncRNA, causes the activity of SE to be dysregulated.
Xinyu Hu, Jianfeng Wu, Yong Feng, Hongxia Ma, Erbao Zhang, Chang Zhang, Qi Sun, Tingting Wang, Yizhi Ge, Dan Zong, Wei Chen, Xia He   +11 more
semanticscholar   +1 more source

METTL16 promotes hepatocellular carcinoma progression through downregulating RAB11B-AS1 in an m6A-dependent manner

Cellular & Molecular Biology Letters, 2022
Background The molecular mechanisms driving hepatocellular carcinoma (HCC) remain largely unclear. As one of the major epitranscriptomic modifications, N 6 -methyladenosine (m 6 A) plays key roles in HCC.
Y. Dai, Yong-da Liu, J. Li, Mei-ting Chen, Meihui Huang, Fang Wang, Qing-song Yang, Ji-hang Yuan, Shulun Sun   +8 more
semanticscholar   +2 more sources

N6-methyladenosine modification of OIP5-AS1 promotes glycolysis, tumorigenesis, and metastasis of gastric cancer by inhibiting Trim21-mediated hnRNPA1 ubiquitination and degradation

Gastric Cancer, 2023
Background Opa-interacting protein 5 antisense transcript 1 (OIP5-AS1) has been demonstrated to play vital roles in development and progression of tumors such as gastric cancer (GC).
R. Xie, Long-fei Liu, Xian-zhou Lu, Chengjian He, Hongyi Yao, Guoxin Li   +5 more
semanticscholar   +1 more source

GATA6-AS1 Regulates Intestinal Epithelial Mitochondrial Functions, and its Reduced Expression is Linked to Intestinal Inflammation and Less Favourable Disease Course in Ulcerative Colitis

Journal of Crohn's & Colitis, 2023
Background and Aims Widespread dysregulation of long non-coding RNAs [lncRNAs] including a reduction in GATA6-AS1 was noted in inflammatory bowel disease [IBD].
K. Sosnovski, T. Braun, A. Amir, Danielle Moshel, M. BenShoshan, K. VanDussen, N. Levhar, H. Abbas-egbariya, K. Beider, Rakefet Ben-Yishay, S. Asad Ali, S. Moore, S. Kugathasan, I. Abramovich, E. G. Saar, B. Weiss, I. Barshack, E. Gottlieb, Tamar Geiger, S. Ben-Horin, I. Ulitsky, J. Hyams, L. Denson, Y. Haberman   +23 more
semanticscholar   +1 more source

Will I love my second baby as much as my first? Prevalence and psychosocial correlates of maternal‐fetal relationship anxiety for second‐time mothers

Infant Mental Health Journal: Infancy and Early Childhood, Volume 44, Issue 4, Page 541-553, July 2023., 2023
Abstract Most mothers have more than one child. Second‐time mothers may worry about whether they will love the second baby as much as their first child. The current study examined mothers’ maternal‐fetal relationship anxiety (MFRA) to their second baby, the prediction of mother‐infant bonding (MIB) and infant‐mother attachment security post‐partum, and
Brenda L. Volling, Lin Tan, Lauren Rosenberg, Lauren R. Bader   +3 more
wiley   +1 more source

TMEM44-AS1 promotes esophageal squamous cell carcinoma progression by regulating the IGF2BP2-GPX4 axis in modulating ferroptosis

Cell Death Discovery, 2023
The long non-coding RNA (lncRNA) TMEM44-AS1 is a novel lncRNA whose pro-carcinogenic role in gastric cancer and glioma has been demonstrated. However, its function in esophageal squamous cell carcinoma (ESCC) is unknown. In this study, we identified that
Ruotong Yang, Junhu Wan, Liwei Ma, Fuyou Zhou, Zhengwu Yang, Zhuofang Li, Mingyuan Zhang, Liang Ming   +7 more
semanticscholar   +1 more source

Differential effects of the LncRNA RNF157-AS1 on epithelial ovarian cancer cells through suppression of DIRAS3- and ULK1-mediated autophagy

Cell Death and Disease, 2023
Analyses of several databases showed that the lncRNA RNF157 Antisense RNA 1 (RNF157-AS1) is overexpressed in epithelial ovarian cancer (EOC) tissues. In our study, suppressing RNF157-AS1 strikingly reduced the proliferation, invasion, and migration of ...
P. Xu, Sujuan Xu, Haiyue Pan, Chencheng Dai, Yiran Xu, Luyao Wang, Yu Cong, Huilin Zhang, Jian Cao, Lili Ge, X. Jia   +10 more
semanticscholar   +1 more source

Hypoxia-induced lncRNA STEAP3-AS1 activates Wnt/β-catenin signaling to promote colorectal cancer progression by preventing m6A-mediated degradation of STEAP3 mRNA

Molecular Cancer, 2022
Background Hypoxia, a typical hallmark of solid tumors, exhibits an essential role in the progression of colorectal cancer (CRC), in which the dysregulation of long non-coding RNAs (lncRNAs) is frequently observed.
Li Zhou, Jingwen Jiang, Zhao Huang, P. Jin, Liyuan Peng, Maochao Luo, Zhe Zhang, Yan Chen, N-N Xie, Wei Gao, E. Nice, Jingqiang Li, Haifang Chen, Canhua Huang   +13 more
semanticscholar   +1 more source

Downregulation of MEIS1 mediated by ELFN1-AS1/EZH2/DNMT3a axis promotes tumorigenesis and oxaliplatin resistance in colorectal cancer

Signal Transduction and Targeted Therapy, 2022
Oxaliplatin is widely used in the frontline treatment of colorectal cancer (CRC), but an estimated 50% of patients will eventually stop responding to treatment due to acquired resistance.
Yimin Li, Yaqi Gan, Jiaxin Liu, Juanni Li, Zhengwei Zhou, Ruotong Tian, Ruizheng Sun, Jiaqi Liu, Qing Xiao, Yuanyuan Li, P. Lu, Yulong Peng, Yuqian Peng, Guang Shu, Gang Yin   +14 more
semanticscholar   +1 more source

Linking spatial economics and sequencing economics for the Osaka tourism agglomeration

Regional Science Policy &Practice, Volume 14, Issue 3, Page 610-626, June 2022., 2022
Abstract An agglomeration is an organization composed of its segments such as infrastructure and institutions. Sequencing economics discusses the sequential process analysis of building the segments of an agglomeration. The concept of ‘economies of sequence’ can be defined as the selection of any two segments from among the set of segments of an ...
Akifumi Kuchiki
wiley   +1 more source