Results 101 to 110 of about 55,528,302 (308)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Boletín III, año 3, n. 23, junio 1995 [PDF]
, 1995 Revista mensual de la Universidad Carlos III de MadridContiene: Órganos de gobierno: Acuerdos de la Comisión Gestora. — Docencia: El ministro de Educación inauguró el Edificio Agustín de Betancourt; La licenciatura en Humanidades, primeta en la ...
Universidad Carlos III de Madrid
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Toward a Sovereign Afghanistan
, 2011 Focusing on four key issue areas relevant to the immediate and near future of Afghanistan including governance and economy, identity, reconciliation and reintegration, and the region and macro region, the Liechtenstein Institute on Self-Determination ...
Liechtenstein Institute on Self-Determination
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Boletín III, año 3, n. 22, marzo 1995 [PDF]
, 1995 Revista mensual de la Universidad Carlos III de MadridContiene: Órganos de gobierno: Acuerdos de la Comisión Gestora. — Claustro Constituyente: La aprobación de los Estatutos.
Universidad Carlos III de Madrid
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Boletín III, año 0, n. 0, diciembre 1991 [PDF]
, 1991 Revista mensual de la Universidad Carlos III de MadridContiene: Editorial: La Comisión Gestora saluda a los lectores. — La Comisión Gestora: La Comisión Gestora Ampliada. — Las comisiones delegadas. — Fundación Carlos III: La Fundación Universidad Carlos
Universidad Carlos III de Madrid
core
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Boletín III, año 2, n. 8, enero 1993 [PDF]
, 1993 Revista mensual de la Universidad Carlos III de MadridContiene: Órganos de gobierno: Acuerdos de la Comisión Gestora. — Docencia: Artículo de Eduardo López-Aranguren, catedrático de sociología; Las estadísticas de la Universidad. — Investigación: Becas y
Universidad Carlos III de Madrid
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source