A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Studies on the Determination of Selenium and Tellurium (III)
GOTO, Hidehiro +2 more
openaire +2 more sources
The global inverse fractional conductivity problem. [PDF]
Covi G, Railo J, Zimmermann P.
europepmc +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
A sensitive spectrophotometric method for the determination of iron with tiron and a cationic surfactant, cetylpyridinium chloride, at pH 5.6 is reported.
Tiwari, M +3 more
core
Pyrrole-modified gold nanoparticle structure for dual UV-vis and smartphone-based colorimetric detection of hexavalent chromium in food and environmental samples. [PDF]
Ali MR +8 more
europepmc +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Evaluation of postoperative pain associated with different working length determination methods: a randomised clinical study. [PDF]
Nalci Calik G +3 more
europepmc +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Characterization and performance of aluminum (III)-complex as an active material for potentiometric sensor. [PDF]
Fawzy KH, Zayed MA, Frag EY.
europepmc +1 more source

