Cytokine and nitric oxide levels in patients with sepsis--temporal evolvement and relation to platelet mitochondrial respiratory function. [PDF]
The levels of nitric oxide (NO) and various cytokines are known to be increased during sepsis. These signaling molecules could potentially act as regulators and underlie the enhancement of mitochondrial function described in the later phase of sepsis ...
Fredrik Sjövall +4 more
doaj +5 more sources
Urban PM2.5 Induces Cellular Toxicity, Hormone Dysregulation, Oxidative Damage, Inflammation, and Mitochondrial Interference in the HRT8 Trophoblast Cell Line [PDF]
Objective: Epidemiological studies have found air pollution to be a driver of adverse pregnancy outcomes, including gestational diabetes, low term birth weight and preeclampsia. It is unknown what biological mechanisms are involved in this process.
Åsa Nääv +11 more
doaj +2 more sources
Bioenergetic bypass using cell-permeable succinate, but not methylene blue, attenuates metformin-induced lactate production [PDF]
Background Metformin is the most common pharmacological treatment for type 2 diabetes. It is considered safe but has been associated with the development of lactic acidosis under circumstances where plasma concentrations exceed therapeutic levels ...
Sarah Piel +6 more
doaj +2 more sources
К биографии Асандра: путь к престолу / To the biography of Asander: way to the throne
Трудно найти более яркую личность на боспорском троне, чем Асандр. Родившись простым гражданином, он не только смог оттеснить на время от престола законный дом Митридатидов, но и навязал свою волю всевластному Риму.
Чореф М.М. / Choref M.M.
doaj +2 more sources
Correlation of mitochondrial respiration in platelets, peripheral blood mononuclear cells and muscle fibers [PDF]
There is a growing interest for the possibility of using peripheral blood cells (including platelets) as markers for mitochondrial function in less accessible tissues.
Emil Westerlund +14 more
doaj +2 more sources
Cellular alterations identified in pluripotent stem cell-derived midbrain spheroids generated from a female patient with progressive external ophthalmoplegia and parkinsonism who carries a novel variation (p.Q811R) in the POLG1 gene [PDF]
Variations in the POLG1 gene encoding the catalytic subunit of the mitochondrial DNA polymerase gamma, have recently been associated with Parkinson’s disease (PD), especially in patients diagnosed with progressive external ophthalmoplegia (PEO). However,
Margarita Chumarina +12 more
doaj +2 more sources
Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency [PDF]
Mitochondrial complex I deficiency is the most common respiratory chain defect in mitochondrial disease in children and currently there is no effective treatment.
Johannes K. Ehinger +14 more
doaj +2 more sources
A rapid assessment of post-disclosure experiences of urban HIV-positive and HIV-negative school-aged children in Kenya. [PDF]
There has been limited involvement of HIV-negative children in HIV disclosure studies; most studies conducted on the effects of disclosure on children have been with HIV-positive children and HIV-positive mother-child dyads.
Gachanja G.
europepmc +10 more sources
К ВОПРОСУ О ВЫДЕЛЕНИИ ЦЕНТРАЛЬНОАЗИАТСКОЙ ДИНАСТИЧЕСКОЙ ЛИНИИ БОСПОРСКОЙ АРИСТОКРАТИИ [PDF]
В центре внимания — династическая история Боспорского царства на рубеже эр. Принимая во внимание мнение о царе Асандре как родоначальнике новой сармато-иранской династии, следует полагать, что члены этого клана опирались на родственные им сарматские ...
Ярцев, С.В.
doaj +1 more source
This study was aimed to induce and produce a polyploidy Robinia pseudoacacia seedling by different concentrations of colchicine (0.0%, 0.5%, 1.0%, 1.5%, and 2.0%) in various exposure times (12, 24 and 48 h), using in two experiments.
Suliman & Asander
doaj +1 more source

