Results 51 to 60 of about 911 (134)

FIGURE 5 from Low Exposures to Amphibole or Serpentine Asbestos in Germline <i>Bap1</i>-mutant Mice Induce Mesothelioma Characterized by an Immunosuppressive Tumor Microenvironment

<p>IHC staining for CD39 (top; diffuse brown stain) and Ccr2 (bottom; punctate stain) in crocidolite-induced and chrysotile-induced MMs from <i>Bap1^+/−</i> mice. Arrows indicate examples of cells positively stained for Ccr2.</p>
Joseph R. Testa, Kathy Cai, Andres J. Klein-Szanto, Hatice U. Osmanbeyoglu, Parham Hadikhani, Mitchell Cheung, Maggie Ruan, Eleonora Sementino, Yuwaraj Kadariya   +8 more
openaire   +1 more source

FIGURE 3 from Low Exposures to Amphibole or Serpentine Asbestos in Germline <i>Bap1</i>-mutant Mice Induce Mesothelioma Characterized by an Immunosuppressive Tumor Microenvironment

<p>Quantification of M2 macrophages in the TIME of asbestos-induced MMs from <i>Bap1^+/−</i> mice using an Aperio scanner, and IHC depicting arginase and iNOS staining of MM from asbestos-treated <i>Bap1^+/⁻</i> mice.
Joseph R. Testa, Kathy Cai, Andres J. Klein-Szanto, Hatice U. Osmanbeyoglu, Parham Hadikhani, Mitchell Cheung, Maggie Ruan, Eleonora Sementino, Yuwaraj Kadariya   +8 more
openaire   +1 more source

FIGURE 1 from Low Exposures to Amphibole or Serpentine Asbestos in Germline <i>Bap1</i>-mutant Mice Induce Mesothelioma Characterized by an Immunosuppressive Tumor Microenvironment

<p>MM formation induced by crocidolite or chrysotile asbestos in mice with germline <i>Bap1</i> heterozygous mutation. MM formation induced by minimal exposure to crocidolite (<b>A</b> and <b>B</b>). <b>A,</b><i>Bap1^+/−</i> and <i>Bap1<sup>+/+</sup ...
Joseph R. Testa, Kathy Cai, Andres J. Klein-Szanto, Hatice U. Osmanbeyoglu, Parham Hadikhani, Mitchell Cheung, Maggie Ruan, Eleonora Sementino, Yuwaraj Kadariya   +8 more
openaire   +1 more source

FIGURE 4 from Low Exposures to Amphibole or Serpentine Asbestos in Germline <i>Bap1</i>-mutant Mice Induce Mesothelioma Characterized by an Immunosuppressive Tumor Microenvironment

<p>Triple indirect IF of crocidolite- and chrysotile-induced MMs from <i>Bap1^+/−</i> mice. IF staining showing tumor cells as well as M1 and M2 macrophages in crocidolite- and chrysotile-induced MMs from 2 <i>Bap1^+/−</i> mice.
Joseph R. Testa, Kathy Cai, Andres J. Klein-Szanto, Hatice U. Osmanbeyoglu, Parham Hadikhani, Mitchell Cheung, Maggie Ruan, Eleonora Sementino, Yuwaraj Kadariya   +8 more
openaire   +1 more source

Case Report: Whispers of the serpent: exploring uncommon imaging features in primary hepatic malignant mesothelioma. [PDF]

Front Med (Lausanne)
Li G, Hong S, He T, Xu J.
europepmc   +1 more source

FIGURE 7 from Low Exposures to Amphibole or Serpentine Asbestos in Germline <i>Bap1</i>-mutant Mice Induce Mesothelioma Characterized by an Immunosuppressive Tumor Microenvironment

<p>Preliminary clinical connections of mouse findings based on NCI human MM RNA-seq and germline mutation data (<a href="#bib16" target="_blank">16</a>). <b>A,</b> Comparison of <i>CCL2</i> mRNA expression levels based on <i>BAP1</i> germline mutation status in 100 MM samples from the NCI cohort ...
Joseph R. Testa, Kathy Cai, Andres J. Klein-Szanto, Hatice U. Osmanbeyoglu, Parham Hadikhani, Mitchell Cheung, Maggie Ruan, Eleonora Sementino, Yuwaraj Kadariya   +8 more
openaire   +1 more source

Nitric Acid Leaching for Magnesium Extraction from Asbestos Ore Waste: From DoE to Predictive Modeling and Cost-Efficient Optimization. [PDF]

Molecules
Ivanov NS, Kholkin OS, Abilmagzhanov AZ, Adelbayev IE, Oparin SK, Ivanova N, Kudryashov V.   +6 more
europepmc   +1 more source

Supplementary Table S1 from Low Exposures to Amphibole or Serpentine Asbestos in Germline <i>Bap1</i>-mutant Mice Induce Mesothelioma Characterized by an Immunosuppressive Tumor Microenvironment

<p>Primary antibodies used for IHC, IF, and immunoblot analyses</p>
Joseph R. Testa, Kathy Cai, Andres J. Klein-Szanto, Hatice U. Osmanbeyoglu, Parham Hadikhani, Mitchell Cheung, Maggie Ruan, Eleonora Sementino, Yuwaraj Kadariya   +8 more
openaire   +1 more source

Comparative analysis of asbestos body and fiber content in formalin-fixed vs. paraffin-embedded lung tissue. [PDF]

Front Public Health
Kuhn BK, Vrugt B, Low A, Goodman JE, Attanoos R.   +4 more
europepmc   +1 more source

Supplementary Figure S6 from Low Exposures to Amphibole or Serpentine Asbestos in Germline <i>Bap1</i>-mutant Mice Induce Mesothelioma Characterized by an Immunosuppressive Tumor Microenvironment

<p>IHC staining for WT1 (purple) and SMA (brown in top panels; teal in bottom panels) in representative crocidolite-induced and chrysotile-induced MMs from Bap1+/- mice. WT1 stains MM cells, whereas SMA stains CAFs, the latter typically more abundant in chrysotile-induced than crocidolite-induced MMs, as in the examples shown here.</p>
Joseph R. Testa, Kathy Cai, Andres J. Klein-Szanto, Hatice U. Osmanbeyoglu, Parham Hadikhani, Mitchell Cheung, Maggie Ruan, Eleonora Sementino, Yuwaraj Kadariya   +8 more
openaire   +1 more source